MAP2K1 antibody

Principal name

MAP2K1 antibody

Alternative names for MAP2K1 antibody

MAPKK 1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK1, PRKMK1, MAP kinase kinase 1, Dual specificity mitogen-activated protein kinase kinase 1

SwissProt ID

P31938 (Mouse), Q01986 (Rat), Q02750 (Human)

Gene ID

5604 (MAP2K1), 26395 (Map2k1), 170851

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Mky (Monkey), Xen (Xenopus), Frog, Por (Porcine), Rb (Rabbit), Ze (Zebrafish), Hst (Hamster)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Dot blot (Dot), Luminex (LMNX)

Background of MAP2K1 antibody

MEK1, a MAP2K type protein kinase, is a member of the Ras MAPK pathway. This pathway modulates the activity of transcription factors, structural proteins and other protein kinases, leading to biological responses such as cell proliferation and differentiation. MEK1 contains a proline-rich segment that is recognized by the scaffold protein MEK binding partner-1 (MP1). MP1 associates with non-phosphorylated MEK1, forming a complex which associates with and phosphorylates MAP kinases ERK1 and 2. Additionally, MEK1 signaling is reported to have a strong negative effect on myogenic differentiation antigen (MYOD) activity via a mechanism involving the binding of MEK1 to the nuclear MYOD transcriptional complex. MEK1 is phosphorylated by several kinases, including Raf1, c-Mos and MEKK1. PAK1 also phosphorylates MEK1 resulting in enhancement of MEK's interaction with Raf-1. Constitutive activation of MEK1 results in cellular transformation; thus, it is a likely target for pharmacologic intervention in proliferative disease. MEK inhibitors have been studied for clinical management of colon cancer and inhibition of viral replication in host cells. MEK1 is a substrate for the anthrax lethal factor (LF).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, Clone , clone OTIE1 (formerly E1)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506006) Mouse IgG1 OTIE1 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  anti-MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI1F5 (formerly 1F5)  
Immunohistochemical staining of paraffin-embedded colon tissue within the normal limits using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500644, Dilution 1:50) Mouse IgG1 OTI1F5 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  anti-MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI1C1 (formerly 1C1)  
Immunohistochemical staining of paraffin-embedded prostate tissue within the normal limits using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500672, Dilution 1:50) Mouse IgG2b OTI1C1 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI2D4 (formerly 2D4)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505702) Mouse IgG2a OTI2D4 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI2H3 (formerly 2H3)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505703) Mouse IgG2b OTI2H3 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI2G5 (formerly 2G5)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505704) Mouse IgG2b OTI2G5 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI1E5 (formerly 1E5)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505705) Mouse IgG2a OTI1E5 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI3B4 (formerly 3B4)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505728) Mouse IgG2a OTI3B4 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI2D2 (formerly 2D2)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505729) Mouse IgG2a OTI2D2 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI2B7 (formerly 2B7)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505742) Mouse IgG1 OTI2B7 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI2B2 (formerly 2B2)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505745) Mouse IgG2a OTI2B2 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI2A1 (formerly 2A1)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505763) Mouse IgG2b OTI2A1 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI2A9 (formerly 2A9)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505764) Mouse IgG2b OTI2A9 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI3H5 (formerly 3H5)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505765) Mouse IgG2b OTI3H5 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI4H8 (formerly 4H8)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505766) Mouse IgG2b OTI4H8 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI4F1 (formerly 4F1)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505767) Mouse IgG2b OTI4F1 Purified Can, Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI3H3 (formerly 3H3)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505768) Mouse IgG1 OTI3H3 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI4H1 (formerly 4H1)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505770) Mouse IgG2b OTI4H1 Purified Can, Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI4B1 (formerly 4B1)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505774) Mouse IgG2a OTI4B1 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MAP2K1 antibody

  MAP2K1 (MEK1) mouse monoclonal antibody, clone OTI4E4 (formerly 4E4)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-MAP2K1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505775) Mouse IgG2a OTI4E4 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

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