MAP3K3 antibody

Principal name

MAP3K3 antibody

Alternative names for MAP3K3 antibody

MAPKKK3, MEKK3, MEK kinase 3, MAPK/ERK kinase kinase 3, Mitogen-activated protein kinase kinase kinase 3

SwissProt ID

Q61084 (Mouse), Q99759 (Human)

Gene ID

4215 (MAP3K3), 26406 (Map3k3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of MAP3K3 antibody

MAP3K3(Mitogen-activated protein kinase kinase kinase 3), also known as MAP/ERK KINASE KINASE 3, MEKK3 or MAPKKK3, is an enzyme that in humans is encoded by the MAP3K3 gene. MAP3K3 is contiguously distal to LYK5 on chromosome 17 (Puffenberger et al., 2007). By yeast 2-hybrid analysis of a mouse T-cell cDNA library, Uhlik et al. (2003) showed that a C-terminal fragment of mouse Osm (CCM2) interacted with Mekk3, which activates p38 in response to sorbitol-induced hyperosmotic conditions. Mekk3 and Osm colocalized in the cytoplasmic compartment of cotransfected cells, and the Mekk3-Osm complex was recruited to Rac1 and cytoskeletal actin-containing membrane ruffles in response to sorbitol treatment. Protein interaction assays showed that Osm interacted directly with the Mekk3 substrate Mkk3 (MAP2K3), with actin, and with both GDP- and GTP-loaded Rac1. Uhlik et al. (2003) concluded that the RAC1-OSM-MEKK3-MKK3 complex is required for regulation of p38 activity in response to osmotic shock.

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MAP3K3 antibody

  Rabbit polyclonal anti-MAP3K3 antibody  
Western blot analysis of extracts from HepG2 cells, using MAP3K3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MAP3K3 antibody

  Rabbit Polyclonal Anti-MAP3K3 Antibody  
Western blot analysis on HepG2 cell lysate using MAP3K3 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MAP3K3 antibody

Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Serum Ms P, WB
50 µl / €470.00
  Acris Antibodies GmbH

MAP3K3 antibody

Western blot analysis of extracts from HepG2 cells, using MAP3K3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €230.00
  Assay Biotech

MAP3K3 antibody

Western blot analysis of extracts from HepG2 cells, using MAP3K3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

MAP3K3 - human gene knockout kit via CRISPR

MAP3K3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MAP3K3 - human gene knockout kit via CRISPR

MAP3K3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAP3K3 - human gene knockout kit via CRISPR

MAP3K3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAP3K3 - human gene knockout kit via CRISPR

MAP3K3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Map3k3 - mouse gene knockout kit via CRISPR

Map3k3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Map3k3 - mouse gene knockout kit via CRISPR

Map3k3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Map3k3 - mouse gene knockout kit via CRISPR

Map3k3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Map3k3 - mouse gene knockout kit via CRISPR

Map3k3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MAP3K3 (full length, N-term HIS tag, transcript variant 2)

  Purified recombinant protein of Homo sapiens mitogen-activated protein kinase kinase kinase 3 (MAP3K3), transcript variant 2 , full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
MAP3K3 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

MAP3K3 overexpression lysate

MAP3K3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MAP3K3 (mGFP-tagged) - Human mitogen-activated protein kinase kinase kinase 3 (MAP3K3), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, MAP3K3 (mGFP-tagged) - Human mitogen-activated protein kinase kinase kinase 3 (MAP3K3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, MAP3K3 (Myc-DDK tagged) - Human mitogen-activated protein kinase kinase kinase 3 (MAP3K3), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, MAP3K3 (Myc-DDK tagged) - Human mitogen-activated protein kinase kinase kinase 3 (MAP3K3), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Map3k3 (GFP-tagged) - Mouse mitogen-activated protein kinase kinase kinase 3 (Map3k3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Map3k3 (GFP-tagged) - Mouse mitogen-activated protein kinase kinase kinase 3 (Map3k3), 200 uL, >10^7 TU/mL  
200 µl / €1,280.00
  OriGene Technologies, Inc.

Lenti ORF particles, Map3k3 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase kinase kinase 3 (Map3k3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Map3k3 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase kinase kinase 3 (Map3k3), 200 uL, >10^7 TU/mL  
200 µl / €1,150.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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