MAPK9 / JNK2 antibody

Principal name

MAPK9 / JNK2 antibody

Alternative names for MAPK9 / JNK2 antibody

JNK-55, PRKM9, MAP kinase 9, Mitogen-activated protein kinase 9, Stress-activated protein kinase JNK2, c-Jun N-terminal kinase 2

SwissProt ID

P45984 (Human), P49186 (Rat), P79996 (Chick), Q9WTU6 (Mouse), Q9WTU6-2

Gene ID

5601 (MAPK9), 50658 (Mapk9), 26420

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Bt (Bat), Bov (Bovine), Eq (Equine), Hst (Hamster), Mky (Monkey), Por (Porcine), Prim (Primate), Rb (Rabbit), Bear, GP (Guinea Pig), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of MAPK9 / JNK2 antibody

The stress-activated protein kise/Jun-amino-termil kise SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, growth factors and GPCR agonists. As with the other MAPKs, the core sigling unit is composed of a MAPKKK, typically MEKK1-MEKK4, or by one of the mixed lineage kises (MLKs), which phosphorylate and activate MKK4/7. Upon activation, MKKs phosphorylate and activate the SAPK/JNK kise. Stress sigls are delivered to this cascade by small GTPases of the Rho family (Rac, Rho, cdc42). Both Rac1 and cdc42 mediate the stimulation of MEKKs and MLKs. Altertively, MKK4/7 can be activated in a GTPase-independent mechanism via stimulation of a germil center kise (GCK) family member. There are three SAPK/JNK genes each of which undergoes altertive splicing, resulting in numerous isoforms. SAPK/JNK, when active as a dimer, can translocate to the nucleus and regulate transcription through its effects on c-Jun, ATF-2, and other transcription factors.

General readings

Kyriakis J M., et al. (1999) J Biol Chem. 274: 5259-62Whitmarsh., et al. (1998) Trends Biochem Sci. 23: 481-5.

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  2. Highly Validated (6)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MAPK9 / JNK2 antibody

  MAPK9 (JNK2) mouse monoclonal antibody, clone OTI2H3 (formerly 2H3)  
Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-MAPK9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505869) Mouse IgG1 OTI2H3 Purified Hu P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

MAPK9 / JNK2 antibody

  MAPK9 (JNK2) mouse monoclonal antibody, clone OTI2D11 (formerly 2D11)  
Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-MAPK9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505877) Mouse IgG1 OTI2D11 Purified Can, Hu, Mky, Ms, Rt P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

MAPK9 / JNK2 antibody

  MAPK9 (JNK2) mouse monoclonal antibody, clone OTI2G3 (formerly 2G3)  
Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-MAPK9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505909) Mouse IgG1 OTI2G3 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

MAPK9 / JNK2 antibody

  MAPK9 (JNK2) mouse monoclonal antibody, clone OTI4D1 (formerly 4D1)  
Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-MAPK9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505910) Mouse IgG1 OTI4D1 Purified Can, Hu, Ms ICC/IF, P, WB
0.1 ml / €350.00
  OriGene Technologies, Inc.

TrueMAB

MAPK9 / JNK2 antibody

  MAPK9 (JNK2) mouse monoclonal antibody, clone OTI1A1 (formerly 1A1)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-MAPK9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505911) Mouse IgG1 OTI1A1 Purified Can, Hu, Mky, Ms, Rt ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

MAPK9 / JNK2 (1-425) antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 1C1-3A8 Purified Hu E, P, WB
50 µg / €420.00
  Acris Antibodies GmbH

MAPK9 / JNK2 antibody

  Anti-MAPK9 Rabbit Polyclonal Antibody  
Western blot analysis of Raw264.7 cell, mouse brain and heart tissue using TA322064 (MAPK9 Antibody) at dilution 1/200 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

7 Item(s)

per page
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