MAPKAP Kinase-2 antibody

Principal name

MAPKAP Kinase-2 antibody

Alternative names for MAPKAP Kinase-2 antibody

MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MK2, MAPKAPK2, MAP kinase-activated protein kinase 2

SwissProt ID

P49137 (Human), P49138 (Mouse), P49139 (Rabit)

Gene ID

9261 (MAPKAPK2), 17164 (Mapkapk2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Hst (Hamster), Chk (Chicken), Rb (Rabbit), Xen (Xenopus), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine), Ye (Yeast)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Dot blot (Dot), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of MAPKAP Kinase-2 antibody

Stress-activated serine/threonine-protein kinase involved in cytokines production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates. Phosphorylates serine in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue. Phosphorylates ALOX5, CDC25B, CDC25C, ELAVL1, HNRNPA0, HSF1, HSP27/HSPB1, KRT18, KRT20, LIMK1, LSP1, PABPC1, PARN, PDE4A, RCSD1, RPS6KA3, TAB3 and TTP/ZFP36. Mediates phosphorylation of HSP27/HSPB1 in response to stress, leading to dissociate HSP27/HSPB1 from large small heat-shock protein (sHsps) oligomers and impair their chaperone activities and ability to protect against oxidative stress effectively. Involved in inflammatory response by regulating tumor necrosis factor (TNF) and IL6 production post-transcriptionally: acts by phosphorylating AU-rich elements (AREs)-binding proteins ELAVL1, HNRNPA0, PABPC1 and TTP/ZFP36, leading to regulate the stability and translation of TNF and IL6 mRNAs. Phosphorylation of TTP/ZFP36, a major post-transcriptional regulator of TNF, promotes its binding to 14-3-3 proteins and reduces its ARE mRNA affinity leading to inhibition of dependent degradation of ARE-containing transcript. Also involved in late G2/M checkpoint following DNA damage through a process of post-transcriptional mRNA stabilization: following DNA damage, relocalizes from nucleus to cytoplasm and phosphorylates HNRNPA0 and PARN, leading to stabilize GADD45A mRNA. Involved in toll-like receptor signaling pathway (TLR) in dendritic cells: required for acute TLR-induced macropinocytosis by phosphorylating and activating RPS6KA3.

  1. Quick-Filters:
  2. Highly Validated (2)
  3. Overnight Delivery (1)

Items 1 to 20 of 61 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MAPKAP Kinase-2 antibody

Immunoperoxidase of monoclonal antibody to MAPKAPK2 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] Mouse IgG2b 2B3 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MAPKAP Kinase-2 antibody

Immunoperoxidase of monoclonal antibody to MAPKAPK2 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] Mouse IgG2a 3B8 Purified Hu, Ms, Rt E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MAPKAP Kinase-2 antibody

AP32810PU-N  (0.5 µg/ml) staining of MEF lysates (35µg protein in RIPA buffer), from double KO mice in second and third lanes and rescued by introduction of MK2 gene in second lane. Primary incubation was 2 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, IP, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 (44-55) antibody

HEK293 overexpressing Mouse MK2 fused to GFP or overexpressing MK5 fused to GFP and probed with AP32810PUN (0.5 μg/ml) in the left panel and with AP32811PU-N (0.5 μg/ml) in the right panel. Goat Aff - Purified Hu, Ms, Rt E, IP, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

Western blot analysis of extracts from COS cells, using MAPKAPK2 (Ab-272) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-2 antibody

Anti-MAPKAP Kinase 2 polyclonal antibody detects MK2 in unstimulated human HeLa whole cell lysate by WB. Polyclonal rabbit-anti-MAPKAP Kinase 2 used at 1:2000 to detect 20 ug of whole cell lysate containing MK2. Rabbit Aff - Purified Chk, Hst, Hu, Ms, Rb, Rt, Xen, Ze E, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-2 antibody

Host: Rabbit; Target Name: MAPKAPK2; Sample Tissue: A549 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-2 antibody

WB Suggested Anti-MAPKAPK2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-2 antibody

MAPKAP Kinase-2 Rabbit Aff - Purified Bov, Can, Hst, Hu, Ms, Rt IP, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pThr334 antibody

MAPKAP Kinase-2 Rabbit Aff - Purified Hu WB
0.1 mg / €460.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pThr334 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using MAPKAPK-2 pThr334 antibody AP02538PU Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pThr334 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using MAPKAPK-2 pThr334 antibody AP02538PU Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
50 µl / €240.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

Immunofluorescence staining of methanol-fixed HeLa cells using MAPKAPK-2 antibody (Red). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €270.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

Immunofluorescence staining of methanol-fixed HeLa cells using MAPKAPK-2 antibody (Red). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
50 µl / €230.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

Immunohistochemistry (IHC)analyzesof MAPKAPK-2 antibody (Cat.-No.: AP06619PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pSer272 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu Dot, P

Regular Price: 0.4 ml / €370.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

Immunohistochemistry (IHC) analyzes of MAPKAPK-2 antibody (Cat.-No.: AP21090PU-N) in paraffin-embedded human heart tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

Immunohistochemistry (IHC) analyzes of MAPKAPK-2 antibody (Cat.-No.: AP21135PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pSer272 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using MAPKAPK2 (Phospho-Ser272) antibody AP55823PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €340.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pSer272 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using MAPKAPK2 (Phospho-Ser272) antibody AP55823PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µl / €270.00
  Acris Antibodies GmbH

Items 1 to 20 of 61 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  • LinkedIn