MAPKAP Kinase-2 antibody

Principal name

MAPKAP Kinase-2 antibody

Alternative names for MAPKAP Kinase-2 antibody

MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MK2, MAPKAPK2, MAP kinase-activated protein kinase 2

SwissProt ID

P49137 (Human), P49138 (Mouse), P49139 (Rabit)

Gene ID

9261 (MAPKAPK2), 17164 (Mapkapk2)

Available reactivities

Bov (Bovine), Can (Canine), Hst (Hamster), Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Rb (Rabbit), Xen (Xenopus), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine), Ye (Yeast)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Dot blot (Dot), ELISA (detection) (E(detection))

Background of MAPKAP Kinase-2 antibody

MAPKAP kinase-2 (or MK2) is an acronym for mitogen-activated protein kinase-activated protein kinase-2. This enzyme is phosphorylated and activated by Erks and p38 MAPK in vitro. While multiple residues of MK2 are phosphorylated in vivo in response to stress, only four of the residues Thr25, Thr222, Ser272 and Thr334 are phosphorylated by p38 in an in vitro kinase assay. MK2 is serine-threonine protein kinase that contains a proline rich sequence and two putative SH3-binding sites. MK2 phosphorylates downstream components on a consensus Pro-X-Ser/Thr-Pro motif. The bestcharacterized MK2 substrate is hsp27. Although unknown, the physiological function of MK2 may be to increase stress resistance. MK2 is an essential component in the inflammatory response that regulates biosynthesis of TNF-α at a posttranscriptional level and MK2 is rapidly phosphorylated and activated in response to cytokines, stress and chemotactic factors.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MAPKAP Kinase-2 antibody

AP32810PU-N  (0.5 µg/ml) staining of MEF lysates (35µg protein in RIPA buffer), from double KO mice in second and third lanes and rescued by introduction of MK2 gene in second lane. Primary incubation was 2 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, IP, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 (44-55) antibody

HEK293 overexpressing Mouse MK2 fused to GFP or overexpressing MK5 fused to GFP and probed with AP32810PUN (0.5 μg/ml) in the left panel and with AP32811PU-N (0.5 μg/ml) in the right panel. Goat Aff - Purified Hu, Ms, Rt E, IP, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

  Rabbit polyclonal MAPKAPK2 (Ab-272) antibody  
Western blot analysis of extracts from COS cells, using MAPKAPK2 (Ab-272) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-2 antibody

  Rabbit polyclonal MAPKAP Kinase 2 antibody  
Anti-MAPKAP Kinase 2 polyclonal antibody detects MK2 in unstimulated human HeLa whole cell lysate by WB. Polyclonal rabbit-anti-MAPKAP Kinase 2 used at 1:2000 to detect 20 ug of whole cell lysate containing MK2. Rabbit Aff - Purified Chk, Hst, Hu, Ms, Rb, Rt, Xen, Ze E, IP, WB
0.1 mg / €356.00
  OriGene Technologies, Inc.

MAPKAP Kinase-2 antibody

  Phospho-MAPKAPK2-T334 Rabbit Polyclonal Antibody  
Western blot analysis of extracts from Hela cells, using Phospho-MAPKAPK2-T334 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-2 antibody

  Rabbit Polyclonal Anti-MAPKAPK2 Antibody  
Host: Rabbit; Target Name: MAPKAPK2; Sample Tissue: A549 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-2 antibody

  Rabbit Polyclonal Anti-MAPKAPK2 Antibody  
WB Suggested Anti-MAPKAPK2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-2 antibody

MAPKAP Kinase-2 Rabbit Aff - Purified Bov, Can, Hst, Hu, Ms, Rt IP, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pThr334 antibody

MAPKAP Kinase-2 Rabbit Aff - Purified Hu WB
0.1 mg / €460.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pThr334 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using MAPKAPK-2 pThr334 antibody AP02538PU Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pThr334 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using MAPKAPK-2 pThr334 antibody AP02538PU Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
50 µl / €240.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

Immunofluorescence staining of methanol-fixed HeLa cells using MAPKAPK-2 antibody (Red). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

Immunofluorescence staining of methanol-fixed HeLa cells using MAPKAPK-2 antibody (Red). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
50 µl / €240.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

Immunohistochemistry (IHC)analyzesof MAPKAPK-2 antibody (Cat.-No.: AP06619PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pSer272 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu Dot, P

Regular Price: 0.4 ml / €370.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

Immunohistochemistry (IHC) analyzes of MAPKAPK-2 antibody (Cat.-No.: AP21090PU-N) in paraffin-embedded human heart tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 antibody

Immunohistochemistry (IHC) analyzes of MAPKAPK-2 antibody (Cat.-No.: AP21135PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pSer272 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using MAPKAPK2 (Phospho-Ser272) antibody AP55823PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €340.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pSer272 antibody

Immunohistochemical analysis of paraffin-embedded human brain tissue using MAPKAPK2 (Phospho-Ser272) antibody AP55823PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µl / €270.00
  Acris Antibodies GmbH

MAPKAP Kinase-2 pThr334 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using MAPKAPK2 (Phospho-Thr334) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

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