MAPKAP Kinase-3 antibody

Principal name

MAPKAP Kinase-3 antibody

Alternative names for MAPKAP Kinase-3 antibody

MAPK-activated protein kinase 3, MAPKAPK-3, MAPKAPK3, MAP kinase-activated protein kinase 3

SwissProt ID

Q16644 (Human), Q3SYZ2 (Bovin), Q3UMW7 (Mouse), Q66H84 (Rat)

Gene ID

7867 (MAPKAPK3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Chicken, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of MAPKAP Kinase-3 antibody

This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

1. Zakowski,V., Keramas,G., Kilian,K., Rapp,U.R. and Ludwig,S., et al.
Mitogen-activated 3p kinase is active in the nucleus
2. Knebel,A., Haydon,C.E., Morrice,N. and Cohen,P., et al.
Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways
3. Simkhovich,B.Z., Abdishoo,S., Poizat,C., Hale,S.L., Kedes,L.H. and Kloner,R.A.
Gene activity changes in ischemically preconditioned rabbit heart gene: discovery array study
4. Tanoue,T., Maeda,R., Adachi,M. and Nishida,E., et al.
Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions
5. Neufeld,B., Grosse-Wilde,A., Hoffmeyer,A., Jordan,B.W., Chen,P., Dinev,D., Ludwig,S. and Rapp,U.R.
Serine/Threonine kinases 3pK and MAPK-activated protein kinase 2 interact with the basic helix-loop-helix transcription factor E47 and repress its transcriptional activity
6. , McLaughlin M.M., Kumar S., McDonnell P.C., Van Horn S., Lee J.C., Livi G.P., Young P.R.
Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase.
7. , Sithanandam G., Latif F., Duh F.-M., Bernal R., Smola U., Li H., Kuzmin I., Wixler V., Geil L., Shrestha S., et al.
3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene region.
8. , Sithanandam G., Latif F., Duh F.-M., Bernal R., Smola U., Li H., Kuzmin I., Wixler V., Geil L., Shrestha S., et al.
Mol. Cell. Biol. 16:1880-1880(1996).
9. , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
10. , Neufeld B., Grosse-Wilde A., Hoffmeyer A., Jordan B.W., Chen P., Dinev D., Ludwig S., Rapp U.R.
Serine/Threonine kinases 3pK and MAPK-activated protein kinase 2 interact with the basic helix-loop-helix transcription factor E47 and repress its transcriptional activity.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MAPKAP Kinase-3 antibody

Immunoperoxidase of monoclonal antibody to MAPKAPK3 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml] Mouse IgG2a 2B5 Purified Hu, Ms E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MAPKAP Kinase-3 antibody

Western blot analysis of extracts from COLO205 cells, using MAPK3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-3 antibody

WB Suggested Anti-MAPKAPK3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-3 antibody

WB Suggested Anti-MAPKAPK3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human kidney Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-3 antibody

Western blot analysis on COLO205 cell lysate using MAPK3 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MAPKAP Kinase-3 antibody

Immunohistochemistry (IHC) analyzes of3pK antibody (Cat.-No.: AP06739PU-N) in paraffin-embedded human skeletal muscle tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MAPKAP Kinase-3 antibody

MAPKAP Kinase-3 Mouse Serum Hu E
50 µl / €290.00
  Abnova Taiwan Corp.

MAPKAP Kinase-3 antibody

MAPKAP Kinase-3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

MAPKAP Kinase-3 antibody

Western Blot analysis of MAPKAPK3 expression in transfected 293T cell line (H00007867-T02) by MAPKAPK3 MaxPab polyclonal antibody.

Lane 1: MAPKAPK3 transfected lysate(43.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

MAPKAP Kinase-3 antibody

MAPKAPK3 monoclonal antibody (M01), clone 3F4 Western Blot analysis of MAPKAPK3 expression in HeLa ( Cat # L013V1 ). Mouse IgG2a 3F4 Purified Hu, Ms E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MAPKAP Kinase-3 antibody

MAPKAP Kinase-3 Mouse IgG2a 1C3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MAPKAP Kinase-3 antibody

MAPKAPK3 monoclonal antibody (M06), clone 4B11 Western Blot analysis of MAPKAPK3 expression in HL-60 ( Cat # L014V1 ). Mouse IgG2a 4B11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MAPKAP Kinase-3 antibody

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using MAPK3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

MAPKAP Kinase-3 antibody

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using MAPK3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

MAPKAP Kinase-3 (C-term) antibody

Human HepG2; WB Suggested Anti-MAPKAPK3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate; MAPKAPK3 antibody - C-terminal region (ARP60321_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

MAPKAP Kinase-3 (C-term) antibody

Human kidney; WB Suggested Anti-MAPKAPK3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human kidney; MAPKAPK3 antibody - C-terminal region (ARP60322_P050) in Human kidney cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

MAPKAP Kinase-3 antibody

MAPKAP Kinase-3 Chicken Aff - Purified Hu WB
50 µg / €520.00
  Novus Biologicals Inc.

MAPKAP Kinase-3 antibody

Immunohistochemistry: 3pK Antibody [NB100-92388] - Immunohistochemistry (IHC) analyzes of3pK (R319)  antibody in paraffin-embedded human skeletal muscle  tissue. Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

MAPKAP Kinase-3 antibody

MAPKAP Kinase-3 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

MAPKAP Kinase-3 antibody

MAPKAP Kinase-3 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

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