MARCKS antibody
Principal name
MARCKS antibody
Alternative names for MARCKS antibody
Myristoylated alanine-rich C-kinase substrate, MACS, PRKCSL
Ncbi ID
NP_002347.5, 9606, 5874, 10116, NP_002347, NM_002356, ACE87588.1, NP_032564.1
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Background of MARCKS antibody
Actin binding protein MARCKS (myristoylated alanine-rich C kise substrate) is a major substrate of PKC, and alterations in PKC-MARCKS-actin axis are critical to several biological processes such as motility, proliferation, invasion, adhesion, cell spreading phagocytosis, secretion and membrane trafficking. Intracellular MARCKS is normally attached to cytoplasmic face of plasma membrane and when phosphorylated by activated PKC, MARCKS translocates from plasma membrane to cytoplasm. MARCKS regulates cell movement by controlling actin cytoskeleton homeostasis and filopodium/lamellipodium formation. MARCKS binds to F-actin, but not to monomeric G-actin, independently of its phosphorylation status and when unphosphorylated, it induces cell migration. MAPK8 can phosphorylate MARCKS which leads to induction of actin bundles formation/stabilization followed by reduction in actin plasticity and restricted cell movement including neurol/cancer cell migration. MARCKS has also been proposed to be involved in coupling the PKC and calmodulin sigling systems. MARCKS is implicated in the pathogenesis of various maligncies such as cancer of pituitary, thyroid, breast, colon, and small intestine as well as melanoma, glioblastoma multiforme cancer and cholangiocarcinoma.
General readings
1. Rodriguez Peña MJ et al. MARCKS Protein Is Phosphorylated and Regulates Calcium Mobilization during Human Acrosomal Exocytosis. PLoS One 8:e64551 (2013). WB ; Human . PubMed: 23704996





























- Quick-Filters:
- Cited (1)
- Highly Validated (1)
Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
---|---|---|---|---|---|---|---|
AM31095PU-N | MARCKS antibody |
||||||
![]() |
Mouse | IgG1 | 2C2 | Purified | Hu, Ms | E, ICC/IF, P, WB |
50 µg /
€420.00
|
Acris Antibodies GmbH | |||||||
![]() |
Highly validated antibody! |
||||||
TA309164 | MARCKS antibody |
||||||
Rabbit Anti-MARCKS (Ser152,156) Antibody (Phospho-Specific) | |||||||
![]() |
Rabbit | IgG | Purified | Rt | WB |
0.1 ml /
€383.00
|
|
OriGene Technologies, Inc. | |||||||
TA314169 | MARCKS antibody |
||||||
Rabbit polyclonal MARCKS (Ser162) antibody(Phospho-specific) | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
TA314170 | MARCKS antibody |
||||||
Rabbit polyclonal MARCKS (Ser158) antibody(Phospho-specific) | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms | E, WB |
0.1 ml /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
TA327803 | MARCKS antibody |
||||||
Rabbit Polyclonal Phospho-MARCKS (Ser158) Antibody (Phospho-specific) | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
TA327863 | MARCKS antibody |
||||||
Rabbit Polyclonal MARCKS Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
TA333248 | MARCKS antibody |
||||||
Phospho-MARCKS-S158 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
|
||
OriGene Technologies, Inc. | |||||||
TA333249 | MARCKS antibody |
||||||
Phospho-MARCKS-S162 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
|
||
OriGene Technologies, Inc. | |||||||
TA333250 | MARCKS antibody |
||||||
Phospho-MARCKS-S170 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu |
0.1 mg /
€335.00
|
||
OriGene Technologies, Inc. | |||||||
TA336534 | MARCKS antibody |
||||||
Rabbit Polyclonal MARCKS Antibody | |||||||
![]() |
Rabbit | Purified | Rt | ICC/IF, WB |
0.1 ml /
€393.00
|
||
OriGene Technologies, Inc. | |||||||
![]() |
|||||||
AP00301PU-N | MARCKS pSer152/156 antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | WB |
0.1 ml /
€430.00
|
||
Acris Antibodies GmbH | |||||||
AP01344PU-N | MARCKS antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | WB |
0.1 mg /
€350.00
|
||
Acris Antibodies GmbH | |||||||
AP02531PU-N | MARCKS pSer158 antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, WB |
0.1 mg /
€320.00
|
||
Acris Antibodies GmbH | |||||||
![]() |
|||||||
AP02531PU-S | MARCKS pSer158 antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, WB |
50 µg /
€240.00
|
||
Acris Antibodies GmbH | |||||||
![]() |
|||||||
AP02758PU-N | MARCKS antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms | WB |
0.1 mg /
€320.00
|
||
Acris Antibodies GmbH | |||||||
AP02758PU-S | MARCKS antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms | WB |
50 µg /
€240.00
|
||
Acris Antibodies GmbH | |||||||
AP02779PU-N | MARCKS antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, WB |
0.1 mg /
€320.00
|
||
Acris Antibodies GmbH | |||||||
![]() |
|||||||
AP02779PU-S | MARCKS antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, WB |
50 µg /
€240.00
|
||
Acris Antibodies GmbH | |||||||
![]() |
|||||||
AP09469PU-N | MARCKS pSer170 antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu | P, WB |
0.1 mg /
€320.00
|
||
Acris Antibodies GmbH | |||||||
![]() |
|||||||
AP09469PU-S | MARCKS pSer170 antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu | P, WB |
50 µg /
€240.00
|
||
Acris Antibodies GmbH | |||||||
![]() |