MARCO antibody

Principal name

MARCO antibody

Alternative names for MARCO antibody

macrophage receptor with collagenous structure, Scavenger Receptor

SwissProt ID

Q60754 (Mouse), Q9UEW3 (Human), Q9WUB9 (Mesau)

Gene ID

17167 (Marco), 8685 (MARCO)

Available reactivities

Ms (Mouse), Hst (Hamster), Hu (Human), Bov (Bovine), Rt (Rat)

Available hosts

Rat, Mouse, Rabbit

Available applications

Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Functional assay (FN)

Background of MARCO antibody

The scavenger receptors (SRs) expressed by macrophages are thought to play an important role in the immune response against bacteria by mediating ligand binding and phagocytosis. SRs can be divided into three different classes based upon their structural properties, which are termed SR-A, SR-B and SR-C. SRs-A are homotrimeric glycoproteins composed of 77 kDa monomers subdivided into 3 types.. The molecular structure of MARCO resembles that of SR-A type I, containing a triple-helical collagenous domain and a scavenger receptor cysteine-rich (SRCR) domain at the C terminus. MARCO is only expressed in some subpopulations of macrophages, although it’s expression can be strongly upregulated during infection or LPS treatment. Furthermore, MARCO is, like sinusoidal endothelial cell markers DC-SIGNR, LYVE-1 and stabilin-2, expressed by sinusoidal endothelial cells in lymph node. MARCO expressed by alveolar macrophages seems to play an important role in response to inhaled particles and airborne pathogens.

General readings

Wright, A.K., et al. J. Leukoc. Biol. 86(3):479-489(2009)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Arredouani, M.S., et al. J. Immunol. 175(9):6058-6064(2005)
Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)
Seta, N., et al. Arthritis Rheum. 44(4):931-939(2001)

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MARCO (420-431) antibody

MARCO Mouse IgG3 PLK-1 Purified Bov, Hu C, F, FN, ICC/IF, IP, WB
0.1 mg / €450.00
  Acris Antibodies GmbH

MARCO (N-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsillitis tissue reacted with MARCO Antibody (N-term) Cat.-No AP52609PU-N, which was peroxidase conjugated to the secondary antibody and followed by DAB staining.This data demonstrates the use of MARCO Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MARCO antibody

Staining of mouse peritoneal macrophages with RAT ANTI MOUSE MARCO-FITC (SM1756F) Rat IgG1 ED31 FITC Ms F
0.1 mg / €480.00
  Acris Antibodies GmbH

MARCO antibody

Staining of mouse peritoneal macrophages with RAT ANTI MOUSE MARCO: FITC (SM1756FS). Rat IgG1 ED31 FITC Ms F
50 µg / €360.00
  Acris Antibodies GmbH

MARCO antibody

MARCO Rat IgG1 ED31 Purified Ms C, F
0.25 mg / €580.00
  Acris Antibodies GmbH

MARCO antibody

MARCO Rat IgG1 ED31 PE Ms F
100 Tests / €580.00
  Acris Antibodies GmbH

MARCO antibody

Human PANC1; WB Suggested Anti-MARCO Antibody Titration: 0.2-1 ug/ml. Positive Control: PANC1 cell lysate. MARCO is supported by BioGPS gene expression data to be expressed in PANC1.; MARCO antibody - N-terminal region (ARP41580_P050) in Human PANC1 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

MARCO (C-term) antibody

MARCO Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

MARCO antibody

Staining of mouse peritoneal macrophages with RAT ANTI MOUSE MARCO: FITC Rat IgG1 ED31 FITC Ms F
50 µg / €400.00
  Novus Biologicals Inc.

MARCO antibody

MARCO Mouse IgM PAL-1 Aff - Purified Hst C, F, IP, P
0.125 mg / €360.00
  Novus Biologicals Inc.

MARCO antibody

Western Blot: MARCO Antibody [NBP1-59543] - This Anti-MARCO antibody was used in Western Blot of PANC1       tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

11 Item(s)

per page
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