MARK1 antibody

Principal name

MARK1 antibody

Alternative names for MARK1 antibody

Serine/threonine-protein kinase MARK1, MARK, MAP/Microtubule Affinity-Regulating Kinase 1

SwissProt ID

O08678 (Rat), Q8VHJ5 (Mouse), Q9P0L2 (Human)

Gene ID

4139 (MARK1), 226778 (Mark1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Bov (Bovine), Can (Canine), Eq (Equine)

Available hosts

Rabbit, Goat

Available applications

Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of MARK1 antibody

MARK is a family of kinases that is known for its involvement in establishing cell polarity and in phosphorylating tau protein during Alzheimer neurodegeneration. Expression of MARK causes the phosphorylation of MAPs at their KXGS motifs, thereby detaching MAPs from the microtubules and thus facilitating the transport of particles. This occurs without impairing the intrinsic activity of motors because the velocity during active movement remains unchanged. In primary retinal ganglion cells, transfection with tau leads to the inhibition of axonal transport of mitochondria, APP vesicles, and other cell components which leads to starvation of axons and vulnerability against stress. This transport inhibition can be rescued by phosphorylating tau with MARK

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MARK antibody

Immunohistochemical analysis of MARK staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt, Ze ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

MARK antibody

Immunohistochemical analysis of MARK staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt, Ze ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

MARK antibody

Immunohistochemical analysis of MARK staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt, Ze ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

MARK1 antibody

Western blot analysis of extracts from HeLa cells, using MARK antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MARK1 antibody

Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Bov, Can, Eq, Hu
50 µg / €379.00
  OriGene Technologies, Inc.

MARK1 (N-term) antibody

Brain, caduate: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

MARK1 (N-term) antibody

Brain, cortex: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

MARK1 (N-term) antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with MARK1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MARK1 (C-term) antibody

The anti-MARK1 C-term Pab is used in Western blot to detect MARK1 in, from left to right, Hela, T47D, and mouse brain cell line/ tissue lysate. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MARK1 antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with MARK1 polyclonal antibody ( Cat # PAB2698 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. Rabbit Hu, Ms E, P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

MARK1 antibody

MARK1 Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

MARK1 antibody

MARK1 Goat Ms, Rt E
0.1 mg / €390.00
  Abnova Taiwan Corp.

MARK1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MARK1/2/3/4 (Ab-215) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

MARK1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MARK1/2/3/4 (Ab-215) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

MARK1 antibody

Western blot analysis of extracts from HeLa cells, using MARK Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

MARK1 antibody

Western blot analysis of extracts from HeLa cells, using MARK Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

MARK1 antibody

MARK1 Rabbit IgG Hu ICC/IF, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

MARK1 antibody

MARK1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

MARK1 antibody

MARK1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
50 µg / €290.00
  Novus Biologicals Inc.

MARK1 antibody

Immunohistochemistry-Paraffin: MARK1 Antibody [NBP1-82799] - Immunohistochemistry-Paraffin: MARK1 Antibody [NBP1-82799] Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

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