MASP-2 antibody

Principal name

MASP-2 antibody

Alternative names for MASP-2 antibody

Mannose-,Mannan-binding lectin serine protease 2, MBL-associated serine protease 2, MAP19

SwissProt ID

O00187 (Human), Q91WP0 (Mouse), Q9JJS8 (Rat)

Gene ID

10747 (MASP2), 17175 (Masp2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of MASP-2 antibody

MASP2, MBL associated serine protease 2, is a serum protease that plays an important role in the activation of the complement system via mannose-binding lectin (MBL). Binding of MBL to carbohydrate groups triggers MASP2 activation by auto-catalytic cleavage which leads to cleavage of C2 and C4, leading to their activation and to the formation of C3 convertase. MASP2 also binds to L-Ficolin and H-Ficolin, and when the complex binds pathogens the MASP is activated. Low MBL levels in serum are associated with increased susceptibility to infection, and an Asp105Gly mutation in MASP2 is associated with low MASP2 levels in serum. Reduced functional levels of MBL are also postulated to be associated with generation of auto in systemic lupus erythematosus, acting through a decreased clearance of apoptotic material. A truncated form of MASP2 that constitutes the amino 185 residues, Map19 is also a component of the MBL-MASP-1 complex.

14 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MASP-2 antibody

Western blot analysis of extracts from K562 cell, using MASP2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MASP-2 antibody

MASP2 MaxPab rabbit polyclonal antibody. Western Blot analysis of MASP2 expression in human spleen. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

MASP-2 antibody

Human Adult Liver; Rabbit Anti-MASP2 Antibody . Catalog Number: ARP41573_P050. Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver . Observed Staining: Cytoplasm in hepatocytes, weak signal, wide tissue distribution . Primary Antibody Concentration: 1:100. Secondary Antibody: Donkey anti-Rabbit-Cy3. Secondary Antibody Concentration: 1:200. Magnification: 20X. Exposure Time: 0.5 – 2.0 sec. Protocol located in Reviews and Data.; MASP2 antibody - N-terminal region (ARP41573_P050) in Human Adult Liver cells using Immunohistochemistry Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

MASP-2 antibody

MASP-2 Rabbit Aff - Purified Hu, Ms WB
50 µg / €350.00
  AVIVA Systems Biology

MASP-2 antibody

Western blot analysis of MASP2 expression in HeLa (A); SP2/0 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

MASP-2 antibody

Western blot analysis of MASP2 expression in HeLa (A); SP2/0 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

MASP-2 antibody

Western blot analysis of MASP2 expression in HeLa (A); SP2/0 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

MASP-2 antibody

Western Blot: MASP2 Antibody [NBP1-58986] - This Anti-MASP2 antibody was used in Western Blot of OVCAR-3     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms WB
50 µg / €440.00
  Novus Biologicals Inc.

MASP-2 antibody

Immunohistochemistry-Paraffin: MASP2 Antibody [NBP1-81258] - Immunohistochemical staining of human pancreas shows moderate cytoplasmic positivity in exocrine glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

MASP-2 antibody

Immunohistochemistry-Paraffin: MASP2 Antibody [NBP1-81259] - Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MASP-2

MASP-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

MASP-2

MASP-2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

MASP2 overexpression lysate

MASP2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

MASP2 overexpression lysate

MASP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

14 Item(s)

per page
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