MCSP antibody

Principal name

MCSP antibody

Alternative names for MCSP antibody

CSPG4, Chondroitin sulfate proteoglycan 4, NG2, Melanoma chondroitin sulfate proteoglycan, Melanoma-associated chondroitin sulfate proteoglycan

SwissProt ID

Q00657 (Rat), Q6UVK1 (Human), Q8VHY0 (Mouse)

Gene ID

1464 (CSPG4), 121021 (Cspg4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of MCSP antibody

NG2 (Neuron Glial Antigen 2), also known as MCSP, and CSPG4 is a chondroitin surface proteoglycan. Chondroitin surface proteoglycans play a role in stabilizing cell-substratum interactions during early events of cell spreading. At large, proteoglycans are important for cell proliferation and migration, and may act as sigl transducers through C-termil cytoplasmic binding to scaffolding or sigling proteins. The NG2 glycoprotein is a type I membrane protein expressed in the developing and adult central nervous system (CNS) by subpopulations of glia including oligodendroglial precursor cells (OPCs), and in the developing CNS additiolly by pericytes. NG2 is located at the apical cell membrane, however it has also been shown to localize to the lamellipodia of astrocytoma upon phosphorylation by PRKCA. Research has found that NG2 may inhibit neurol growth (PMC1571583), and also acts as a proapoptotic receptor.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MCSP antibody

Western Blot: NG2 Antibody (LHM 2) [TA336295] - Western blot analysis of NG2 expression in HeLa whole cell lysate. Mouse IgG1 LHM 2 Purified Hu C, F, ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MCSP antibody

MCSP Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MCSP antibody

MCSP Mouse IgG1 LHM 2 Purified Hu F, ICC/IF, IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

CSPG4 - human gene knockout kit via CRISPR

CSPG4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CSPG4 - human gene knockout kit via CRISPR

CSPG4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CSPG4 - human gene knockout kit via CRISPR

CSPG4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CSPG4 - human gene knockout kit via CRISPR

CSPG4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cspg4 - mouse gene knockout kit via CRISPR

Cspg4 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cspg4 - mouse gene knockout kit via CRISPR

Cspg4 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cspg4 - mouse gene knockout kit via CRISPR

Cspg4 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MCSP

MCSP Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CSPG4 overexpression lysate

CSPG4 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CSPG4 (Myc-DDK tagged) - Human chondroitin sulfate proteoglycan 4 (CSPG4), 200 uL, >10^7 TU/mL

Lenti ORF particles, CSPG4 (Myc-DDK tagged) - Human chondroitin sulfate proteoglycan 4 (CSPG4), 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

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