MDC / CCL22 antibody

Principal name

MDC / CCL22 antibody

Alternative names for MDC / CCL22 antibody

SCYA22, CC chemokine STCP-1, C-C motif chemokine 22, Macrophage-derived chemokine, Small-inducible cytokine A22, Stimulated T-cell chemotactic protein 1

SwissProt ID

O00626 (Human), O88430 (Mouse), Q5I0L5 (Rat)

Gene ID

6367 (CCL22), 20299 (Ccl22)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Chicken, Rat

Available applications

Enzyme Immunoassay (E), Functional assay (FN), Western blot / Immunoblot (WB), Paraffin Sections (P), Neutralisation (NEUT)

Background of MDC / CCL22 antibody

Macrophage-derived chemokine (MDC), also called Chemokine, cc motif, ligand 22 (CCL22) or Small inducible cytokine subfamily A, member 22 (SCY22). MDC is a recently identified member of the CC chemokine family. It is not closely related to other chemokines, sharing most similarity with thymus- and activation-regulated chemokine (TARC), which contains 37% identical amino acids. In addition, MDC gene is mapped to chromosome 16q13, the same position reported for the TARC gene. MDC has the four-cysteine motif and other highly conserved residues characteristic of CC chemokines, but it shares <35% identity with any of the known chemokines. Recombinant MDC was expressed in Chinese hamster ovary cells and purified by heparin-Sepharose chromatography. MDC is highly expressed in macrophages and in monocyte-derived dendritic cells, but not in monocytes, natural killer cells, or several cell lines of epithelial, endothelial, or fibroblast origin. High expression was also detected in normal thymus and less expression in lung and spleen. MDC is thus a unique member of the CC chemokine family that may play a fundamental role in the function of dendritic cells, natural killer cells, and monocytes.

General readings

Wang G., et al. (2009). Cancer. 115(11):2430-7.
Silvano Sozzani., et al. (2000). Journal of Leukocyte Biology. 68:400-404.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MDC / CCL22 antibody

To detect mMDC by direct ELISA (using 100 ul/well antibody solution) a concentration of 0.25-1.0 ug/ml of this antibody is required.  This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2-0.4 ng/well of recombinant mMDC. Rabbit IgG Purified E, WB
50 µg / €325.00
  OriGene Technologies, Inc.

MDC / CCL22 antibody

To detect mMDC by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5 - 2.0 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Murine MDC (TA328536) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant mMDC. Rabbit IgG Purified E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MDC / CCL22 antibody

MDC / CCL22 Rabbit Biotin Ms E, WB
50 µg / €340.00
  Acris Antibodies GmbH

MDC / CCL22 antibody

MDC / CCL22 Rabbit Biotin Ms E, WB
25 µg / €230.00
  Acris Antibodies GmbH

MDC / CCL22 antibody

MDC / CCL22 Rabbit Aff - Purified Ms E, FN, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

MDC / CCL22 antibody

MDC / CCL22 Rabbit Aff - Purified Ms E, FN, WB
50 µg / €230.00
  Acris Antibodies GmbH

MDC / CCL22 antibody

MDC / CCL22 Mouse IgG1 Azide Free Hu E, FN, WB
0.5 mg / €220.00
  Acris Antibodies GmbH

MDC / CCL22 antibody

MDC / CCL22 Rabbit Biotin Hu E, WB
25 µg / €230.00
  Acris Antibodies GmbH

MDC / CCL22 antibody

MDC / CCL22 Rabbit Biotin Hu E, WB
50 µg / €340.00
  Acris Antibodies GmbH

MDC / CCL22 antibody

Western Blot (Reduced) using MDC Antibody Cat.-No PP1049P Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Acris Antibodies GmbH

MDC / CCL22 antibody

Western Blot (Reduced) using MDC Antibody Cat.-No PP1049P Rabbit Aff - Purified Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

MDC / CCL22 antibody

MDC / CCL22 Rabbit Ms, Rt WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

MDC / CCL22 antibody

MDC / CCL22 Rabbit IgG Aff - Purified Ms, Rt WB
0.1 mg / €470.00
  Novus Biologicals Inc.

MDC / CCL22 antibody

MDC / CCL22 Rabbit Purified Ms, Rt WB
0.2 mg / €290.00
  Torrey Pines Biolabs

MDC / CCL22 antibody

MDC / CCL22 Rabbit Azide Free Ms, Rt WB
0.2 mg / €290.00
  Torrey Pines Biolabs

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MDC / CCL22

MDC / CCL22 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

MDC / CCL22

MDC / CCL22 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

MDC / CCL22

MDC / CCL22 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

MDC / CCL22

MDC / CCL22 Mouse > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

MDC / CCL22

MDC / CCL22 Mouse > 98 %
Preparation: .
Purity Detail: >98%, as determined by Coomassie stained SDS-PAGE.

Regular Price: 10 µg / €119.00

Special Price: 10 µg / €99.00

  OriGene Technologies, Inc.

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