MDS1 antibody

Principal name

MDS1 antibody

Alternative names for MDS1 antibody

Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1

SwissProt ID

P38615 (Yeast), Q13465 (Human), Q9Z1L8 (Mouse)

Gene ID

2122 (MECOM), 4197, 14013 (Mecom)

Available reactivities

Hu (Human), Ms (Mouse), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection))

Background of MDS1 antibody

Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. MDS1, first identified as part of a fusion transcript resulting from the t(3;21)(q26;q22), encodes a small protein of unknown function. EVI1 encodes a zinc finger protein inappropriately overexpressed by chromosomal rearrangements. EVI1 and MDS1 are unusual in that they can either encode separate proteins, or they can be expressed as a fusion protein MDS1/EVI1. EVI1 and MDS1/EVI1 have opposite functions as transcription factors.

General readings

Gomez-Benito, M., et al. Br. J. Cancer 103(8):1292-1296(2010)
Meyer, T.E., et al. PLoS Genet. 6 (8) (2010)
Goyama, S., et al. Int. J. Hematol. 91(5):753-757(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010)
Haas, K., et al. Genes Chromosomes Cancer 47(4):288-298(2008)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MDS1 antibody

  Rabbit Polyclonal Anti-MDS1 Antibody  
WB Suggested Anti-MDS1 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1: 312500; Positive Control: Raji cell lysate Rabbit IgG Purified Hu, Ms, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MDS1 (N-term) antibody

Figure 1. Western analysis of extracts from 293 cells using PRDM3 antibody (AM11039PU-N). Mouse IgG1 47AT612.84.88 Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MDS1 (Center) antibody

Western blot analysis of MDS1 Antibody (Center) Cat.-No AP52645PU-N in mouse NIH-3T3 cell line lysates (35ug/lane). This demonstrates the MDS1 antibody detected the MDS1 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MDS1 antibody

MDS1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

MDS1 antibody

Western Blot analysis of MDS1 expression in transfected 293T cell line (H00004197-T01) by MDS1 MaxPab polyclonal antibody.

Lane 1: MDS1 transfected lysate(18.59 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

MDS1 antibody

Western Blot analysis of MDS1 expression in transfected 293T cell line (H00004197-T01) by MDS1 MaxPab polyclonal antibody.

Lane 1: MDS1 transfected lysate(18.59 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

MDS1 antibody

Detection limit for recombinant GST tagged MDS1 is approximately 3ng/ml as a capture antibody. Mouse IgG2b 1E7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MDS1 antibody

Human Raji; WB Suggested Anti-MDS1 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:312500. Positive Control: Raji cell lysate; MDS1 antibody - N-terminal region (ARP38536_T100) in Human Raji cells using Western Blot Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €310.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

Mecom - mouse gene knockout kit via CRISPR

Mecom - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Mecom - mouse gene knockout kit via CRISPR

Mecom - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MDS1

MDS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

MDS1

MDS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

MDS1

MDS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

MDS1

MDS1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

MDS1 293T Cell Transient Overexpression Lysate(Denatured)

MDS1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Mecom (GFP-tagged) - Mouse MDS1 and EVI1 complex locus (Mecom), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Mecom (GFP-tagged) - Mouse MDS1 and EVI1 complex locus (Mecom), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mecom (Myc-DDK-tagged) - Mouse MDS1 and EVI1 complex locus (Mecom), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Mecom (Myc-DDK-tagged) - Mouse MDS1 and EVI1 complex locus (Mecom), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

17 Item(s)

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