MED17 antibody

Principal name

MED17 antibody

Alternative names for MED17 antibody

Mediator complex subunit 17, ARC77, CRSP6, DRIP77, DRIP80, TRAP80, CRSP complex subunit 6, Mediator of RNA polymerase II transcription subunit 17, Cofactor required for Sp1 transcriptional activation subunit 6, Transcriptional coactivator CRSP77, Vitamin D3 receptor-interacting protein complex 80 kDa component, Thyroid hormone receptor-associated protein complex 80 kDa component, Activator-recruited cofactor 77 kDa component

SwissProt ID

P32569 (Yeast), Q5BIR6 (Bovin), Q5ZID1 (Chick), Q8VCD5 (Mouse), Q9NVC6 (Human)

Gene ID

9440 (MED17), 856743 (SRB4)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog, Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of MED17 antibody

In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase. These complexes include CRSP (for cofactor required for Sp1 activation), which is required, in conjunction with TAFIIs, for transcriptional activation by Sp1. CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits, each having an individual molecular mass ranging from 33 to 200 kDa. Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS. CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins. CRSP subunits also associate with larger multimeric co-activator complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex.

General readings

Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Jang, M.K., et al. Mol. Cell 19(4):523-534(2005)
Tomomori-Sato, C., et al. J. Biol. Chem. 279(7):5846-5851(2004)
Sato, S., et al. J. Biol. Chem. 278(17):15123-15127(2003)
Lau, J.F., et al. Mol. Cell. Biol. 23(2):620-628(2003)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MED17 antibody

Immunoperoxidase of monoclonal antibody to CRSP6 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.2 ug/ml] Mouse IgG1 4D4 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MED17 antibody

Human Brain; CRSP6 antibody - N-terminal region (ARP34192_P050) in Human Brain cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

MED17 antibody

WB Suggested Anti-CRSP6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: HepG2 cell lysate; MED17 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Can, Eq, GP, Hu, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

MED17 antibody

Western blot analysis on HT29 cell lysate using MED17 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MED17 antibody

Immunohistochemistry (IHC) analyzes of CRSP77 antibody (Cat.-No.: AP20462PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MED17 (Center) antibody

Western blot analysis of MED17 Antibody (Center) Cat.-No AP52651PU-N in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the MED17 antibody detected the MED17 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MED17 antibody

MED17 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

MED17 antibody

Immunofluorescence of monoclonal antibody to CRSP6 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG1 1B5 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MED17 antibody

Detection of GCN5 by Western blotting using the GCN5 polyclonal antibody ( Cat # PAB1164 ) . Extract of budding yeast was using as antigen. The antiserum was diluted 5000 fold before use. Rabbit E, WB
50 µl / €390.00
  Abnova Taiwan Corp.

MED17 antibody

Western blot analysis of extracts from HT-29 cells, using MED17 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

MED17 antibody

Western blot analysis of extracts from HT-29 cells, using MED17 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

MED17 antibody

Immunohistochemistry: CRSP77 Antibody [NBP1-19617] -  CRSP77 Antibody [NBP1-19617] - paraffin-embedded human brain tissue.. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

MED17 antibody

MED17 Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

MED17 antibody

MED17 Rabbit IgG Aff - Purified Hu, Ms E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MED17

MED17 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

MED17

MED17 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

MED17

MED17 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

17 Item(s)

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