MED27 antibody

Principal name

MED27 antibody

Alternative names for MED27 antibody

CRSP34, CRSP8, Mediator complex 27, CRSP complex subunit 8, Mediator of RNA polymerase II transcription subunit 27, Cofactor required for Sp1 transcriptional activation subunit 8

SwissProt ID

Q2TBN7 (Bovin), Q6P2C8 (Human), Q6Q7J5 (Pig), Q9DB40 (Mouse)

Gene ID

9442 (MED27), 68975 (Med27)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of MED27 antibody

he activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. CRSP8 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. CRSP8 is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

General readings

Malik S., et al. (2000) Mol. Cell. 5:753-760Ryu S., et al. (1999) Nature. 397:446-450

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MED27 antibody

  Rabbit Polyclonal Anti-MED27 Antibody  
WB Suggested Anti-MED27 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

MED27 antibody

  Rabbit polyclonal anti-MED27 antibody  
Western blot analysis of extracts from HeLa cells, using MED27 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MED27 antibody

  Rabbit Polyclonal Anti-CRSP8 Antibody  
WB Suggested Anti-CRSP8 Antibody Titration: 5.0 ug/ml; ELISA Titer: 1: 62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

MED27 - human gene knockout kit via CRISPR

MED27 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MED27 - human gene knockout kit via CRISPR

MED27 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Med27 - mouse gene knockout kit via CRISPR

Med27 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Med27 - mouse gene knockout kit via CRISPR

Med27 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Med27 - mouse gene knockout kit via CRISPR

Med27 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Med27 - mouse gene knockout kit via CRISPR

Med27 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MED27 (1-311, His-tag)

MED27 Human Purified > 80 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

MED27 (1-311, His-tag)

MED27 Human Purified > 80 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Crsp8 (GFP-tagged) - Mouse cofactor required for Sp1 transcriptional activation, subunit 8 (cDNA clone MGC:29026 IMAGE:3585027), 200 uL, >10^7 TU/mL

Lenti ORF particles, Crsp8 (GFP-tagged) - Mouse cofactor required for Sp1 transcriptional activation, subunit 8 (cDNA clone MGC:29026 IMAGE:3585027), 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Crsp8 (Myc-DDK-tagged) - Mouse cofactor required for Sp1 transcriptional activation, subunit 8 (cDNA clone MGC:29026 IMAGE:3585027), 200 uL, >10^7 TU/mL

Lenti ORF particles, Crsp8 (Myc-DDK-tagged) - Mouse cofactor required for Sp1 transcriptional activation, subunit 8 (cDNA clone MGC:29026 IMAGE:3585027), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, Med27 (GFP-tagged) - Mouse mediator complex subunit 27 (Med27), 200 uL, >10^7 TU/mL

Lenti ORF particles, Med27 (GFP-tagged) - Mouse mediator complex subunit 27 (Med27), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Med27 (Myc-DDK-tagged) - Mouse mediator complex subunit 27 (Med27), 200 uL, >10^7 TU/mL

Lenti ORF particles, Med27 (Myc-DDK-tagged) - Mouse mediator complex subunit 27 (Med27), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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