MEIS1 antibody

Principal name

MEIS1 antibody

Alternative names for MEIS1 antibody

Homeobox protein Meis1

SwissProt ID

O00470 (Human), Q60954 (Mouse)

Gene ID

4211 (MEIS1), 17268 (Meis1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of MEIS1 antibody

Hox, Pbx, and Meis families of transcription factors form heteromeric complexes and bind DNA through specific homeobox domains. Hox proteins are involved in regulating tissue patterning during development, and they are also expressed n lineage- and stage-specific patterns during adult ematopoietic ifferentiation and in leukemias. The Hox proteins, which include paralog groups 1 to 10, have a low intrinsic binding affinity for DNA and are instead associated into cooperative DNA binding complexes with Pbx or the Pbx related Meis proteins, which result in an enhanced Hox-DNA binding affinity and an increased selectivity for the binding site. Both Meis1 and 2 (also known as Meis-related gene 1) are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. In addition to binding with Hox proteins, Meis1 also forms heterodimers with the ubiquitously expressed Pbx proteins, including Pbx1, Pbx2 and Pbx3, and these complexes contain distinct DNA-binding specificities.

General readings

Wong P, Iwasaki M, Somervaille TC, So CW, Cleary ML.
Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.
Genes Dev. 2007 Nov 1;21(21):2762-74. Epub 2007 Oct 17. Erratum in: Genes Dev.
PMID: 17942707

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MEIS1 antibody

  Goat Anti-MEIS1 Antibody  
TA305776 (0.1ug/ml) staining of Human Cerebral Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MEIS1 antibody

  Rabbit Polyclonal Anti-MEIS1 Antibody  
WB Suggested Anti-MEIS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Lung Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

MEIS1 antibody

  Rabbit Polyclonal Anti-MEIS1 Antibody  
WB Suggested Anti-MEIS1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, Eq, Hu, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MEIS1 antibody

  Rabbit Polyclonal MEIS1 Antibody  
ELISA: MEIS1 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

MEIS1 antibody

Western blot (WB) analysis of Meis1 antibody (Cat.-No.: AP20611PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MEIS1 antibody

MEIS1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

MEIS1 antibody

MEIS1 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

MEIS1 antibody

MEIS1 polyclonal antibody ( Cat # PAB11460 ) ( 0.1 µg/ml ) staining of human cerebral cortex lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

MEIS1 antibody

Human Lung; WB Suggested Anti-MEIS1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Lung; MEIS1 antibody - middle region (ARP32017_P050) in Human Lung cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

MEIS1 antibody

Human Liver; WB Suggested Anti-MEIS1 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Liver; MEIS1 antibody - C-terminal region (ARP38149_P050) in Human Liver cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

MEIS1 - human gene knockout kit via CRISPR

MEIS1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MEIS1 - human gene knockout kit via CRISPR

MEIS1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MEIS1 - human gene knockout kit via CRISPR

MEIS1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MEIS1 - human gene knockout kit via CRISPR

MEIS1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Meis1 - mouse gene knockout kit via CRISPR

Meis1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Meis1 - mouse gene knockout kit via CRISPR

Meis1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Meis1 - mouse gene knockout kit via CRISPR

Meis1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Meis1 - mouse gene knockout kit via CRISPR

Meis1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MEIS1

MEIS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

MEIS1

MEIS1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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