MEPCE / BCDIN3 antibody

Principal name

MEPCE / BCDIN3 antibody

Alternative names for MEPCE / BCDIN3 antibody

Bin-3 homolog, Bin3 homolog, 7SK snRNA methylphosphate capping enzyme, Bicoid-interacting protein 3 homolog

SwissProt ID

Q7L2J0 (Human), Q8K3A9 (Mouse)

Gene ID

56257 (MEPCE)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Can (Canine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of MEPCE / BCDIN3 antibody

MEPCE belongs to the methyltransferase superfamily and contains one BIN3 domain. It is an S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it. MEPCE is expressed in chronic myeloid leukemia cells, adrenal gland, brain, cerebellum, kidney, lung, mammary gland and testis. It is weakly or not expressed in other tissues.

General readings

Jeronimo C, Forget D, Bouchard A, Li Q, Chua G, Poitras C, Therien C, Bergeron D, Bourassa S, Greenblatt J, Chabot B, Poirier GG, Hughes TR, Blanchette M, Price DH, Coulombe B. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Mol Cell. 2007 Jul 20;27(2):262-74. PMID: 17643375

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  2. Highly Validated (1)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MEPCE / BCDIN3 antibody

Immunohistochemical staining of human rectum shows strong nuclear positivity in glandular cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only. Rabbit IgG Purified Hu E, ICC/IF, P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

MEPCE / BCDIN3 antibody

TA302538 (1µg/ml) staining of Rat Testis lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MEPCE / BCDIN3 antibody

TA305736 (0.3ug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MEPCE / BCDIN3 antibody

Host: Rabbit; Target Name: MEPCE; Sample Tissue: NCI-H226 Whole Cell lysates; Antibody Dilution: 1.0 ug/mlMEPCE is supported by BioGPS gene expression data to be expressed in NCIH226 Rabbit IgG Purified Can, GP, Hu, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

MEPCE / BCDIN3 antibody

293 overexpressing MEPCE and probed with MEPCE polyclonal antibody ( Cat # PAB7372 ) ( mock transfection in first lane), tested by Origene. Goat Hu, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

MEPCE / BCDIN3 antibody

ELISA: MEPCE Antibody [35690002] Rabbit Hu E, P, WB
50 µg / €400.00
  Novus Biologicals Inc.

MEPCE / BCDIN3 antibody

Western Blot: MEPCE Antibody [NB100-93420] -  HEK293 over expressing MEPCE (RC200948) and probed with NB100-93420 (mock transfection in first lane), tested by Origene. Goat IgG Aff - Purified Hu, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

MEPCE / BCDIN3 antibody

Western Blot:  Bin3 Antibody [NBP1-28464]-(0.3g/ml) staining of K562 lysate (35g protein in RIPA buffer) Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MEPCE / BCDIN3

MEPCE / BCDIN3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

MEPCE overexpression lysate

MEPCE overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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