MERIT40 antibody

Principal name

MERIT40 antibody

Alternative names for MERIT40 antibody

C19orf62, NBA1, HSPC142, BRCA1-A complex subunit MERIT40, Mediator of RAP80 interactions and targeting subunit of 40 kDa, New component of the BRCA1-A complex

SwissProt ID

Q08E57 (Bovin), Q3UI43 (Mouse), Q5XIJ6 (Rat), Q9NWV8 (Human)

Gene ID

29086 (BABAM1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), African clawed frog, Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of MERIT40 antibody

Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36. component.

General readings

Zheng Y. et al. (2011) Breast Cancer Res Treat. 127:871-877Solyom S. et al. (2010) Breast Cancer Res Treat. 120:165-168.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MERIT40 antibody

WB Suggested Anti-C19orf62 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Hela cell lysateBABAM1 is supported by BioGPS gene expression data to be expressed in HeLa Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

MERIT40 antibody

Formalin-fixed and paraffin-embedded human brain reacted with HSPC142 Antibody (Center) (Cat.-No AP18061PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu P, WB

Regular Price: 0.4 ml / €370.00

Special Price: 0.4 ml / €231.00

  Acris Antibodies GmbH

MERIT40 antibody

Immunofluorescence of purified MaxPab antibody to HSPC142 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

MERIT40 antibody

MERIT40 Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

MERIT40 antibody

Human HeLa; WB Suggested Anti-C19orf62 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Hela cell lysate. BABAM1 is supported by BioGPS gene expression data to be expressed in HeLa.; C19orf62 antibody - N-terminal region (ARP54986_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

MERIT40 antibody

Western Blot: HSPC142 Antibody [NBP1-56773] - This Anti-C19orf62 antibody was used in Western Blot of Hela tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MERIT40 (transcript variant 2)

MERIT40 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

MERIT40 (transcript variant 1)

MERIT40 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

MERIT40 (1-329, His-tag)

MERIT40 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €940.00
  Acris Antibodies GmbH

MERIT40 (1-329, His-tag)

MERIT40 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

MERIT40

MERIT40 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

MERIT40

MERIT40 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

HSPC142 293T Cell Transient Overexpression Lysate(Denatured)

HSPC142 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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