Merlin antibody

Principal name

Merlin antibody

Alternative names for Merlin antibody

Neurofibromin-2, NF2, SCH, Schwannomin, Schwannomerlin, Moesin-ezrin-radixin-like protein, Schwannomin, Schwannomerlin

SwissProt ID

P35240 (Human), P46662 (Mouse), P59750 (Papan), Q63648 (Rat)

Gene ID

4771 (NF2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Chk (Chicken), Can (Canine), Mky (Monkey)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of Merlin antibody

This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq]. Transcript Variant: This variant (7) lacks two alternate in-frame exons in the 5' coding region and includes an alternate exon in the 3' coding region, compared to variant 1. The resulting protein (isoform 7, also referred to as isoform delE2/3) is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Gutmann DH, Wright DE, Geist RT, Snider WD (1995) Expression of the neurofibromatosis 2 (NF2) gene isoforms during rat embryonic development. Human Molecular Genetics 4:471-478.
Scherer SS, Gutmann DH (1997) Expression of the neurofibromatosis 2 tumor suppressor gene product, merlin, in Schwann cells. J. Neurosci. Res. 46:595-605.

  1. Quick-Filters:
  2. Highly Validated (1)

Items 1 to 20 of 43 total

per page
Page:
  1. 1
  2. 2
  3. 3

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Merlin antibody

Immunofluorescent staining of HeLa cells using anti-NF2 rabbit polyclonal antibody (TA590014). Rabbit IgG Purified Can, Hu, Mky, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Merlin pSer518 antibody

Phospho-specific antibody to NF2 (Merlin) at pS518 was used at a 1:1000 dilution to detect NF2 by WB. Approximately 12 ul of a mouse cardiac myocyte lysate was loaded per lane on a 4-20% Criterion gel for SDS-PAGE. Samples were either mock treated (lane 1) or CLA treated at 4nM, 20 nM or 100 nM (lanes 2, 3 and 4 respectively) for 45'. After washing, a 1:5,000 dilution of HRP conjugated Gt-a-Rabbit IgG  preceded color development using Amersham's substrate system. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Merlin (N-term) antibody

Western blot analysis of Merlin Antibody (N-term) (Cat. #TA324866) in NCI-H460 cell line lysates (35ug/lane). NF2 (arrow) was detected using the purified Pab. Rabbit Hu ICC/IF, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Merlin antibody

Western blot analysis of Merlin phosphorylation expression in IFN-a treated HuvEc whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Merlin pSer518 antibody

Figure 2. Immunofluorescence staining of methanol-fixed HeLa cells using Merlin pSer518 antibody AP02513PU (Red). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

Merlin pSer518 antibody

Figure 2. Immunofluorescence staining of methanol-fixed HeLa cells using Merlin pSer518 antibody AP02513PU (Red). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
50 µl / €240.00
  Acris Antibodies GmbH

Merlin antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using Merlin antibody Cat.-No AP02759PU-N/PU-S. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Acris Antibodies GmbH

Merlin antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using Merlin antibody Cat.-No AP02759PU-N/PU-S. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µl / €230.00
  Acris Antibodies GmbH

Merlin pSer518 antibody

AP07606PU-N NF2 antibody staining of Formalin-Fixed Paraffin-Embedded Human Brain, cortex at 2.5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Hu, Ms E, IP, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Merlin antibody

AP08595PU-N at 5µg/ml staining NF2/Merlin in Zebrafish brain cortex by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Goat IgG Aff - Purified Chk, Hu, Ms, Ze E, P
50 µg / €470.00
  Acris Antibodies GmbH

Merlin antibody

Merlin Goat Aff - Purified Ze E, P
0.1 mg / €340.00
  Acris Antibodies GmbH

Merlin antibody

Western blot (WB) analyzes of Merlin antibody (Cat.-No.: AP20757PU-N) in extracts from HuvEc cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Merlin pSer518 antibody

Western blot (WB) analyzes of p-NF2 antibody (Cat.-No.: AP20869PU-N) in extracts from Jurkat IFN cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Merlin antibody

Immunofluorescence of purified MaxPab antibody to NF2 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Merlin antibody

Immunoprecipitation of NF2 transfected lysate using anti-NF2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with NF2 MaxPab mouse polyclonal antibody (B02) (H00004771-B02). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

Merlin antibody

Merlin Goat Ze E, P
0.1 mg / €400.00
  Abnova Taiwan Corp.

Merlin antibody

Merlin Rabbit Hu, Ms C, E, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

Merlin pSer518 antibody

Western blot analysis of extracts from HuvEc cells treated with IFN-alpha 1000U/ml 18h, using Merlin (Phospho-Ser518) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

Merlin pSer518 antibody

Western blot analysis of extracts from HuvEc cells treated with IFN-alpha 1000U/ml 18h, using Merlin (Phospho-Ser518) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

Merlin pSer10 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Merlin (Phospho-Ser10) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

Items 1 to 20 of 43 total

per page
Page:
  1. 1
  2. 2
  3. 3
  • LinkedIn