MESP1 antibody

Principal name

MESP1 antibody

Alternative names for MESP1 antibody

Mesoderm posterior protein 1

SwissProt ID

P97309 (Mouse), Q9BRJ9 (Human)

Gene ID

55897 (MESP1), 17292 (Mesp1)

Available reactivities

Hu (Human), Can (Canine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of MESP1 antibody

ES-cell-based cardiovascular repair requires an in-depth understanding of the molecular mechanisms underlying the differentiation of cardiovascular ES cells. A candidate cardiovascular-fate inducer is the bHLH transcription factor MesP1 (1,2). As one of the earliest markers, it is expressed specifically in almost all cardiovascular precursors and is required for cardiac morphogenesis (2,3). It was shown that MesP1 is a key factor sufficient to induce the formation of ectopic heart tissue in vertebrates and increase cardiovasculogenesis by ES cells. Electrophysiological analysis showed all subtypes of cardiac ES-cell differentiation (4). MesP1 overexpression and knockdown experiments revealed a prominent function of MesP1 in a gene regulatory cascade, causing Dkk-1-mediated blockade of canonical Wnt-signalling. Independent evidence from ChIP and in vitro DNA-binding studies, expression analysis in wild-type and MesP knockout mice, and reporter assays confirm that Dkk-1 is a direct target of MesP1.

General readings

David,R., (2008) Nat. Cell Biol. 10 (3), 338-345

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MESP1 antibody

  Rabbit Polyclonal Anti-MESP1 Antibody  
WB Suggested Anti-MESP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: 293T cell lysate Rabbit IgG Purified Can, Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

MESP1 antibody

Western blot analysis using MESP1 mAb against MESP1(AA: 1-200)-hIgGFc transfected HEK293 cell lysate. Mouse IgG1 1A3 Ascites Hu E, WB
0.1 ml / €360.00
  Acris Antibodies GmbH

MESP1 antibody

Immunofluorescence staining of cryo-sections of unfixed human foreskin with anti-Human MesP1 Antibody (dilution 1:100) and counter staining of nuclei with Dapi. Note: The specific green MesP1 signal is visible in the epidermis and in dermal blood vessels.The experiment was performed by the research group of Prof. Dr. J. Wilting and Dr. K. Buttler, University Medicine Göttingen, Germany. Rabbit Purified Hu C, ICC/IF, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

MESP1 antibody

Immunofluorescence staining of cryo-sections of unfixed human foreskin with anti-Human MesP1 Antibody (dilution 1:100) and counter staining of nuclei with Dapi. Note: The specific green MesP1 signal is visible in the epidermis and in dermal blood vessels.The experiment was performed by the research group of Prof. Dr. J. Wilting and Dr. K. Buttler, University Medicine Göttingen, Germany. Rabbit Purified Hu C, ICC/IF, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

MESP1 - human gene knockout kit via CRISPR

MESP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MESP1 - human gene knockout kit via CRISPR

MESP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MESP1 - human gene knockout kit via CRISPR

MESP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MESP1 - human gene knockout kit via CRISPR

MESP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MESP1

  Recombinant protein of human mesoderm posterior 1 homolog (mouse) (MESP1)  
MESP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

MESP1

SDS-PAGE analysis of recombinant Human MesP1: Sample was loaded in 15% SDS-polyacrylamide gel and stained with Silver staining. 
Lane 1: Molecular weight marker (kDa). 
Lane 2: Reduced MesP1. Human Purified > 95 % by SDS-PAGE & silver stain Insect cells
50 µg / €600.00
  Acris Antibodies GmbH

MESP1

SDS-PAGE analysis of recombinant Human MesP1: Sample was loaded in 15% SDS-polyacrylamide gel and stained with Silver staining. 
Lane 1: Molecular weight marker (kDa). 
Lane 2: Reduced MesP1. Human Purified > 95 % by SDS-PAGE & silver stain Insect cells
10 µg / €280.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

MESP1 overexpression lysate

MESP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MESP1 (mGFP-tagged)-Human mesoderm posterior 1 homolog (mouse) (MESP1), 200 uL, >10^7 TU/mL

Lenti ORF particles, MESP1 (mGFP-tagged)-Human mesoderm posterior 1 homolog (mouse) (MESP1), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, MESP1 (Myc-DDK-tagged)-Human mesoderm posterior 1 homolog (mouse) (MESP1), 200 uL, >10^7 TU/mL

Lenti ORF particles, MESP1 (Myc-DDK-tagged)-Human mesoderm posterior 1 homolog (mouse) (MESP1), 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Mesp1 (GFP-tagged) - Mouse mesoderm posterior 1 (Mesp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Mesp1 (GFP-tagged) - Mouse mesoderm posterior 1 (Mesp1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Mesp1 (Myc-DDK-tagged) - Mouse mesoderm posterior 1 (Mesp1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Mesp1 (Myc-DDK-tagged) - Mouse mesoderm posterior 1 (Mesp1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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