Hu (Human), Ms (Mouse), Can (Canine), Por (Porcine), Rt (Rat), Bov (Bovine), Chk (Chicken)
Mouse, Goat, Rabbit
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of Methionine synthase / MTR antibody
MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the fil step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. [provided by RefSeq].
Chen LH, Liu ML, Hwang HY, Chen LS, Korenberg J, Shane B. Human methionine synthase. cDNA cloning, gene localization, and expression. J Biol Chem 1997 Feb 7;272(6):3628-34 PMID: 9013615.
NB 100-791 (2µg/ml) staining of Hela lysate (RIPA buffer, 1.4E5 cells per lane). Detected by western blot using chemiluminescence.
Human 721_B; WB Suggested Anti-MTR Antibody Titration: 0.2-1 ug/ml. Positive Control: 721_B cell lysate. MTR is supported by BioGPS gene expression data to be expressed in 721_B.; MTR antibody - C-terminal region (ARP48473_P050) in Human 721_B cells using Western Blot