Methylated Lysine antibody

Principal name

Methylated Lysine antibody

Available reactivities

Av (Birds), Mam (Mammalia)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Frozen Sections (C), Radioimmunoassay (R), Flow Cytometry (F)

Background of Methylated Lysine antibody

Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common posttranscriptional modification of Lysine involves methylation (1). Lysine can be methylated once, twice or three times by lysine methyltransferases. The transfer of methyl groups from S-adenosyl methionine to histones is catalyzed by enzymes known as histone methyltransferases. Histones which are methylated on certain residues can act epigenetically to repress or activate gene expression (1, 2).
The transcriptional repressor SUV39H1 can encode novel enzymes which selectively methylate histone H3 at lysine 9. SUV39H1 places a methyl marker on histone H3, which is then recognized by HP1 through its chromo domain. This model may also explain the stable inheritance of the heterochromatic state (3). Some studies have also speculated a stimulatory role for transcription by methylated histone lyside 4 due to its presence at active transcription sites (4-6).

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Methylated Lysine antibody

Methylated Lysine Rabbit IgG Biotin E, IP, WB
0.4 ml / €430.00
  Acris Antibodies GmbH

Methylated Lysine antibody

Methylated Lysine Rabbit IgG HRP E, WB
0.4 ml / €450.00
  Acris Antibodies GmbH

Methylated Lysine antibody

Western blot analysis of Methylated Lysine in BSA (Left) and Methylated BSA (Right), using a 1/1000 dilution of Methylated Lysine Antibody Cat.-No AP03036SU-N Rabbit IgG Aff - Purified C, E, IP, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

Methylated Lysine antibody

Methylated Lysine Rabbit IgG C, E, F, IP, R, WB
0.1 mg / €560.00
  Abnova Taiwan Corp.

Methylated Lysine antibody

Methylated Lysine Rabbit HRP E, WB
0.2 ml / €550.00
  Novus Biologicals Inc.

Methylated Lysine antibody

Methylated Lysine Rabbit Biotin E, IP, WB
0.4 ml / €450.00
  Novus Biologicals Inc.

Methylated Lysine antibody

Methylated Lysine Rabbit IgG Aff - Purified E, IP, WB
0.4 ml / €450.00
  Novus Biologicals Inc.

7 Item(s)

per page
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