Mevalonate kinase antibody

Principal name

Mevalonate kinase antibody

Alternative names for Mevalonate kinase antibody

MVK, MK

SwissProt ID

P07277 (Yeast), P17256 (Rat), Q03426 (Human), Q5E9T8 (Bovin), Q9R008 (Mouse)

Gene ID

4598 (MVK), 17855 (Mvk), 81727

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Chk (Chicken), Rt (Rat), Ze (Zebrafish), Can (Canine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Mevalonate kinase antibody

MVK is the peroxisomal enzyme mevalote kise. Mevalote is a key intermediate, and mevalote kise a key early enzyme, in isoprenoid and sterol synthesis. Mevalote kise deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobuliemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestil dismay and skin rash.This gene encodes the peroxisomal enzyme mevalote kise. Mevalote is a key intermediate, and mevalote kise a key early enzyme, in isoprenoid and sterol synthesis. Mevalote kise deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobuliemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestil dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.

General readings

Junyent M, Parnell LD, Lai CQ, et al. (2009). Am. J. Clin. Nutr. 90 (3): 686–94.
Samkari A, Borzutzky A, Fermo E, et al. (2010). Pediatrics 125 (4): e964–8.
Hager EJ, Gibson KM (2007). N. Engl. J. Med. 357 (18): 1871–2.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Mevalonate kinase antibody

  Rabbit polyclonal Mevalonate Kinase antibody  
Western blot analysis of extracts from COS-7 cells and COLO205 cells, using Mevalonate Kinase antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Mevalonate kinase antibody

  Rabbit anti-MVK Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using MVK antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Mevalonate kinase antibody

  Rabbit polyclonal Anti-MVK Antibody  
WB Suggested Anti-MVK Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

Mevalonate kinase antibody

  Rabbit polyclonal Anti-MVK Antibody  
WB Suggested Anti-MVK Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

Mevalonate kinase antibody

  Rabbit Polyclonal Anti-MVK Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Raji cells, Primary antibody: (MVK Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Mevalonate kinase antibody

  MVK mouse monoclonal antibody, clone OTI 1D7 (formerly 1D7)  
Anti-MVK mouse monoclonal antibody (TA502934) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MVK(RC201971). Mouse IgG2a OTI 1D7 Purified Hu ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

Mevalonate kinase antibody

The cell lysates of HepG2 (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human MVK antibody (1:500 ~ 1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG3 AT14F6 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

Mevalonate kinase antibody

The cell lysates of HepG2 (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human MVK antibody (1:500 ~ 1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG3 AT14F6 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

Mevalonate kinase antibody

Immunohistochemistry analyzes of MVK antibody (Cat.-No.: AP20432PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Mevalonate kinase antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Mevalonate Kinase Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
50 µg / €230.00
  Assay Biotech

Mevalonate kinase antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Mevalonate Kinase Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

MVK - human gene knockout kit via CRISPR

MVK - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MVK - human gene knockout kit via CRISPR

MVK - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MVK - human gene knockout kit via CRISPR

MVK - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MVK - human gene knockout kit via CRISPR

MVK - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mvk - mouse gene knockout kit via CRISPR

Mvk - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Mvk - mouse gene knockout kit via CRISPR

Mvk - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mvk - mouse gene knockout kit via CRISPR

Mvk - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mvk - mouse gene knockout kit via CRISPR

Mvk - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Mevalonate kinase (transcript variant 1)

  Recombinant protein of human mevalonate kinase (MVK), transcript variant 1  
Mevalonate kinase Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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