mGluR5 / GRM5 antibody

Principal name

mGluR5 / GRM5 antibody

Alternative names for mGluR5 / GRM5 antibody

Metabotropic glutamate receptor 5, GPRC1E, MGLUR5

SwissProt ID

P31424 (Rat), P41594 (Human), Q3UVX5 (Mouse)

Gene ID

2915 (GRM5), 24418 (Grm5), 108071

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Rb (Rabbit), Mky (Monkey), Por (Porcine), Chk (Chicken)

Available hosts

Rabbit, Mouse, Chicken

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of mGluR5 / GRM5 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient . They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical sigls, temperature, or mechanical forces.There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and filly those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and ictivation by second messengers, inward rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Filly, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels .The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast syptic transmission in the CNS. AMPARs are composed of four types of subunits, desigted as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers .

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

mGluR5 / GRM5 antibody

Western blot analysis of rat brain membranes: 1. Anti-mGluR5 (extracellular) antibody, (1:500). 2. Anti-mGluR5 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

AP15645PU mGluR5 antibody staining of Human Brain. Rabbit Purified Bov, Can, Hu, Rb, Rt IP, P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

mGluR5 / GRM5 antibody

AP15645PU mGluR5 antibody staining of Human Brain. Rabbit Purified Bov, Can, Hu, Rb, Rt IP, P, WB
1 ml / €520.00
  Acris Antibodies GmbH

mGluR5 / GRM5 antibody

AP15645PU mGluR5 antibody staining of Human Brain. Rabbit Purified Bov, Can, Hu, Rb, Rt IP, P, WB
0.1 ml / €190.00
  Acris Antibodies GmbH

mGluR5 / GRM5 antibody

Western blot of 10 ug of HEK 293 cells expressing mGluR1a and mGluR5 showing the specific immunolabeling of the ~125k monomer and the ~250k dimers of mGluR1a and mGluR5. Rabbit IgG Purified Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

mGluR5 / GRM5 Mouse IgG2a S75-33 Purified Hu, Ms, Rt C, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

Anti-GRM5 / MGLUR5 antibody IHC of human colon, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

Anti-GRM5 / MGLUR5 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €379.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

Anti-GRM5 / MGLUR5 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P, WB
50 µg / €379.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

Western blot analysis of GRM5 expression in HT-29 cells Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

Western blot analysis with extracts from human A549 cells using mGluR5 / GRM5 antibody (Cat.-No. AP01270PU-N). Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

mGluR5 / GRM5 (C-term) antibody

Western blot analysis of Metabotropic Glutamate Receptor 5 (GPRC1E) antibody (C-term) in mouse brain tissue lysates (35ug/lane). Metabotropic Glutamate Receptor 5 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

mGluR5 / GRM5 (C-term) antibody

mGluR5 antibody staining of Rat globus pallidus. Images courtesy of Dr. Joyce Besheer, UNC. Rabbit IgG Aff - Purified Can, Ms, Rt C, ICC/IF, WB
50 µg / €570.00
  Acris Antibodies GmbH

mGluR5 / GRM5 antibody

mGluR5 staining of pyramidal and granule cell neurons in the hippocampal formation of an adult transgenic Mouse brain (red satining). Green staining is GFP-immunoreactivity under the control of a constitutive actin promoter Chicken Ig Purified Hu, Ms C, ICC/IF
1.0 ml / €440.00
  Acris Antibodies GmbH

mGluR5 / GRM5 antibody

mGluR5 / GRM5 Rabbit Purified Hu C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

mGluR5 / GRM5 antibody

Detection limit for recombinant GST tagged GRM5 is approximately 0.03ng/ml as a capture antibody. Mouse IgG2a 1B3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

mGluR5 / GRM5 antibody

Detection limit for recombinant GST tagged GRM5 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2b 3E7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

mGluR5 / GRM5 antibody

mGluR5 / GRM5 Rabbit Hu, Ms E
0.4 ml / €390.00
  Abnova Taiwan Corp.

mGluR5 / GRM5 antibody

Immunohistochemical staining of GRM5 on formalin fixed, paraffin embedded human brain with GRM5 polyclonal antibody. Rabbit Hu IP, P, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

mGluR5 / GRM5 antibody

Immunofluorescence analysis of LOVO cells, using GRM5 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

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