mGluR5 / GRM5 antibody

Principal name

mGluR5 / GRM5 antibody

Alternative names for mGluR5 / GRM5 antibody

Metabotropic glutamate receptor 5, GPRC1E, MGLUR5

SwissProt ID

P31424 (Rat), P41594 (Human), Q3UVX5 (Mouse)

Gene ID

24418 (Grm5), 108071, 2915 (GRM5)

Available reactivities

Ms (Mouse), Rt (Rat), Hu (Human), Bov (Bovine), Can (Canine), Rb (Rabbit), Mky (Monkey), Por (Porcine), Chk (Chicken)

Available hosts

Rabbit, Mouse, Chicken

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP)

Background of mGluR5 / GRM5 antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient . They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical sigls, temperature, or mechanical forces.There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and filly those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and ictivation by second messengers, inward rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Filly, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels .The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast syptic transmission in the CNS. AMPARs are composed of four types of subunits, desigted as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers .

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

mGluR5 / GRM5 antibody

  Rabbit Polyclonal Anti-mGluR5 (extracellular)  
Western blot analysis of rat brain membranes: 1. Anti-mGluR5 (extracellular) antibody, (1:500). 2. Anti-mGluR5 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

  Rabbit Anti-Metabotropic Glutamate Receptor 5/1a Antibody  
Western blot of 10 ug of HEK 293 cells expressing mGluR1a and mGluR5 showing the specific immunolabeling of the ~125k monomer and the ~250k dimers of mGluR1a and mGluR5. Rabbit IgG Purified Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

  Mouse Monoclonal Anti-mGluR1/5 glutamate receptor Antibody  
mGluR5 / GRM5 Mouse IgG2a S75-33 Purified Hu, Ms, Rt C, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

  Rabbit Polyclonal Anti-GRM5 Antibody (N-Terminus)  
mGluR5 / GRM5 Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €400.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

  Rabbit Polyclonal Anti-GRM5 Antibody (C-Terminus)  
mGluR5 / GRM5 Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

  Rabbit Polyclonal Anti-GRM5 Antibody (C-Terminus)  
mGluR5 / GRM5 Rabbit Aff - Purified Hu P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

  Rabbit Polyclonal Anti-GRM5 Antibody  
Western blot analysis of GRM5 expression in HT-29 cells Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

  Rabbit Polyclonal anti-mGluR5 Antibody  
Human Brain stained with anti-mGluR5 antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

mGluR5 / GRM5 antibody

Western blot analysis with extracts from human A549 cells using mGluR5 / GRM5 antibody (Cat.-No. AP01270PU-N). Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

mGluR5 / GRM5 (C-term) antibody

Western blot analysis of Metabotropic Glutamate Receptor 5 (GPRC1E) antibody (C-term) in mouse brain tissue lysates (35ug/lane). Metabotropic Glutamate Receptor 5 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

mGluR5 / GRM5 (C-term) antibody

mGluR5 antibody staining of Rat globus pallidus. Images courtesy of Dr. Joyce Besheer, UNC. Rabbit IgG Aff - Purified Can, Ms, Rt C, ICC/IF, WB
50 µg / €570.00
  Acris Antibodies GmbH

mGluR5 / GRM5 antibody

mGluR5 staining of pyramidal and granule cell neurons in the hippocampal formation of an adult transgenic Mouse brain (red satining). Green staining is GFP-immunoreactivity under the control of a constitutive actin promoter Chicken Ig Purified Hu, Ms C, ICC/IF
1.0 ml / €500.00
  Acris Antibodies GmbH

mGluR5 / GRM5 antibody

mGluR5 / GRM5 Rabbit Purified Hu C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

mGluR5 / GRM5 antibody

Immunofluorescence analysis of LOVO cells, using GRM5 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

mGluR5 / GRM5 antibody

Immunofluorescence analysis of LOVO cells, using GRM5 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

mGluR5 / GRM5 antibody

Adult mouse cochlear ganglion stained with mGluR5 (green) and Tuj-1 (red). Chicken Aff - Purified Hu, Ms C, ICC/IF
0.1 ml / €210.00
  Neuromics Antibodies

mGluR5 / GRM5 (21-509) antibody

Human metabotropic glutamate receptor 5 (mGluR5) staining of paraffin-embedded human cerebellum sections using 25 µg/mL mouse anti-human mGluR5 monoclonal antibody.  Tissue was stained usin HRP-DAB (brown) and counterstained with hematoxylin (blue).  This antibody specifically recognizes human mGluR5. This antibody has not yet been tested in other species. Mouse IgG2b Purified Hu P
0.1 mg / €340.00
  Neuromics Antibodies

mGluR5 / GRM5 (824-1203) antibody

mGluR1/5 staining of adult rat hippocampus. Mouse IgG1 Supernatant Hu, Ms, Rt C, ICC/IF, IP, WB
0.1 ml / €440.00
  Neuromics Antibodies

mGluR5 / GRM5 Control Peptide

mGluR5 immunoreactivity in rat globus pallidus. Images courtesy of Dr. Joyce Besheer, UNC. Purified
0.1 mg / €310.00
  Neuromics Antibodies

mGluR5 / GRM5 antibody

mGluR5 / GRM5 Rabbit Aff - Purified Ms, Rt WB
0.1 ml / €250.00
  Neuromics Antibodies

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