mGluR6 / GRM6 antibody

Principal name

mGluR6 / GRM6 antibody

Alternative names for mGluR6 / GRM6 antibody

Metabotropic glutamate receptor 6, GPRC1F, MGLUR6

SwissProt ID

O15303 (Human), P35349 (Rat), Q5NCH9 (Mouse), Q863I4 (Rabit)

Gene ID

2916 (GRM6), 24419 (Grm6), 108072

Available reactivities

Hu (Human), Can (Canine), Chk (Chicken), Ms (Mouse), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), Prim (Primate), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Ye (Yeast)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Dot blot (Dot), Frozen Sections (C)

Background of mGluR6 / GRM6 antibody

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

General readings

Hashimoto,T., et al., (1997) Eur. J. Neurosci. 9 (6), 1226-1235

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

mGluR6+7 / GRM6+7 (C-term) antibody

Human brain stained with mGluR6/7 antibody. Rabbit IgG Aff - Purified Chk, Hu, Ms, Prim, Rt ICC/IF, P, WB
0.5 ml / €380.00
  Neuromics Antibodies

mGluR6 / GRM6 (N-term) antibody

Anti-GRM6 / MGLUR6 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €379.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

Anti-GRM6 / MGLUR6 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

Western blot analysis of extracts from mouse brain, using GluR6 antibody (#TA313975).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

Western blot analysis of rat eye lysates: 1. Anti-mGluR6 (extracellular) antibody, (1:200). 2. Anti-mGluR6 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

WB Suggested Anti-GRM6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Small Intestine Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

WB Suggested Anti-GRM6 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

WB Suggested Anti-GRM6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 721_B cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

Western blot analysis on mouse brain cell lysate using mGluR6 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

mGluR6 / GRM6 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

mGluR6 / GRM6 antibody

mGluR6 / GRM6 Mouse IgG1 1A11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

mGluR6 / GRM6 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with GRM6 polyclonal antibody ( Cat # PAB3656 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit IgG Purified Hu E, P
0.4 ml / €390.00
  Abnova Taiwan Corp.

mGluR6 / GRM6 antibody

Immunofluorescence detection of Grm6 in trapezoid body in mouse brain using Grm6 polyclonal antibody ( Cat # PAB12109 ) and anti-rabbit Cy3 conjugated secondary antibodies ( red color ). DAPI was used to counterstain. Rabbit Ms, Rt ICC/IF, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

mGluR6 / GRM6 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using mGluR6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
50 µg / €205.00
  Assay Biotech

mGluR6 / GRM6 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using mGluR6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €310.00
  Assay Biotech

mGluR6 / GRM6 (Center) antibody

Human Small Intestine; WB Suggested Anti-GRM6 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Small Intestine; GRM6 antibody - middle region (ARP31907_P050) in Human Small Intestine cells using Western Blot Rabbit Aff - Purified Can, Chk, Hu, Ms, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

mGluR6 / GRM6 antibody

Human HepG2; Host: Rabbit. Target Name: GRM6. Sample Tissue: HepG2 Whole Cell lysates. Antibody Dilution: 1.0ug/ml.; GRM6 antibody - C-terminal region (ARP32597_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Can, Chk, Hu, Ms, Rb, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

mGluR6 / GRM6 antibody

Human 721_B; WB Suggested Anti-GRM6 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: 721_B cell lysate; GRM6 antibody - N-terminal region (ARP58004_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Can, Chk, Hu, Ms, Rb, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

mGluR6 / GRM6 antibody

Immunofluorescent analysis of mGLUR6 staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4  C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

mGluR6 / GRM6 antibody

Immunofluorescent analysis of mGLUR6 staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4  C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

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