mGluR6 / GRM6 antibody

Principal name

mGluR6 / GRM6 antibody

Alternative names for mGluR6 / GRM6 antibody

Metabotropic glutamate receptor 6, GPRC1F, MGLUR6

SwissProt ID

O15303 (Human), P35349 (Rat), Q5NCH9 (Mouse), Q863I4 (Rabit)

Gene ID

2916 (GRM6), 24419 (Grm6), 108072

Available reactivities

Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Prim (Primate), Ze (Zebrafish), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Ye (Yeast)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of mGluR6 / GRM6 antibody

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

General readings

Hashimoto,T., et al., (1997) Eur. J. Neurosci. 9 (6), 1226-1235

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

mGluR6+7 / GRM6+7 (C-term) antibody

Human brain stained with mGluR6/7 antibody. Rabbit IgG Aff - Purified Chk, Hu, Ms, Prim, Rt ICC/IF, P, WB
0.5 ml / €380.00
  Neuromics Antibodies

mGluR6 / GRM6 (N-term) antibody

  Rabbit Polyclonal Anti-GRM6 Antibody (N-Terminus)  
Anti-GRM6 / MGLUR6 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

  Rabbit Polyclonal Anti-GRM6 Antibody (N-Terminus)  
Anti-GRM6 / MGLUR6 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

  Rabbit polyclonal anti-GluR6 antibody  
Western blot analysis of extracts from mouse brain, using GluR6 antibody (#TA313975).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

  Rabbit Polyclonal Anti-mGluR6 (extracellular)  
Western blot analysis of rat eye lysates: 1. Anti-mGluR6 (extracellular) antibody, (1:200). 2. Anti-mGluR6 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

  Rabbit Polyclonal Anti-GRM6 Antibody  
WB Suggested Anti-GRM6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Small Intestine Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

  Rabbit Polyclonal Anti-GRM6 Antibody  
WB Suggested Anti-GRM6 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

  Rabbit Polyclonal Anti-GRM6 Antibody - N-terminal region  
WB Suggested Anti-GRM6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 721_B cell lysate Rabbit IgG Purified Bov, Can, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

  Rabbit Polyclonal Anti-mGluR6 Antibody  
Western blot analysis on mouse brain cell lysate using mGluR6 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

mGluR6 / GRM6 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using mGluR6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
50 µg / €230.00
  Assay Biotech

mGluR6 / GRM6 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using mGluR6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €330.00
  Assay Biotech

mGluR6 / GRM6 antibody

mGluR6 / GRM6 Rabbit Aff - Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €310.00
  Neuromics Antibodies

mGluR6 / GRM6 (N-term) antibody

mGluR6 staining of Human eye ganglion cells (Formalin-Fixed Paraffin-Embedded) Rabbit IgG Aff - Purified Hu P
50 µg / €520.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

GRM6 - human gene knockout kit via CRISPR

GRM6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

GRM6 - human gene knockout kit via CRISPR

GRM6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

GRM6 - human gene knockout kit via CRISPR

GRM6 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

GRM6 - human gene knockout kit via CRISPR

GRM6 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Grm6 - mouse gene knockout kit via CRISPR

Grm6 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Grm6 - mouse gene knockout kit via CRISPR

Grm6 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Grm6 - mouse gene knockout kit via CRISPR

Grm6 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

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