MHC Class I (RT1Aa) antibody

Principal name

MHC Class I (RT1Aa) antibody

Alternative names for MHC Class I (RT1Aa) antibody

RT1 class I histocompatibility antigen AA alpha chain

SwissProt ID

P16391 (Rat)

Ncbi ID

10116

Available reactivities

Rt (Rat)

Available hosts

Mouse, Rat

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Flow Cytometry (F), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of MHC Class I (RT1Aa) antibody

MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.

General readings

1. Fukumoto, T. et al. (1982). Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and Class I antigens in rat thymus. Eur. J. Immunol. 12: 237-243.
2. Bukovsky, A., et al. (1984). Association of some cell surface antigens of lymphoid cells and cell surface differentiation antigens with early rat pregnancy. Immunology. 52:631-640
3. Osawa, H. et al. (1985). Inhibin of IL-2 dependent proliteration of rat T-lymphoblast by the monoclonal antibody ART62 which reacts with MHC class I antigens.
J. Immunol. 134(6): 3901-3906.
4. Stet, R.J.M. et al. (1987). U9F4: A monoclonal antibody recognizing a rat polymorphic class I determinant.
Transpl. Proc. 19: 3004-3005.
5. Fujikawa, L. S. et al. (1989). Class Ii antigens on retinal vascular endothelium, pericytes, macrophages and lymphocytes of the rat.
Invest. Ophthalmol. Vis. Sci. 30(1): 66-73
6. Zhai, Y. and Knechtle, S. et al. (1998). Two distinct forms of soluble MHC class II molecules synthesized by different mechanisms in normal rat cell in vitro.
Human Immunol. 59: 404-414

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MHC Class I (RT1Aa) (polymorphic) antibody

MHC Class I (RT1Aa) Rat IgG2a R2/15S Supernatant Rt F
5 ml / €330.00
  Acris Antibodies GmbH

MHC Class I (RT1Aa) antibody

Cell Source: Spleen - Percentage of cells stained above control: 97.0% Mouse IgG1 OX-18 Azide Free Rt C, F, IP
1 mg / €620.00
  Acris Antibodies GmbH

MHC Class I (RT1Aa) antibody

Staining of rat spleen cells with MOUSE ANTI RAT RT1A ( CLASS I MONOMORPHIC): FITC (SM311F). Mouse IgG1 OX-18 FITC Rt F
0.1 mg / €430.00
  Acris Antibodies GmbH

MHC Class I (RT1Aa) antibody

MHC Class I (RT1Aa) Mouse IgG1 OX-18 Purified Rt C, F, IP
0.25 mg / €430.00
  Acris Antibodies GmbH

MHC Class I (RT1Aa) antibody

MHC Class I (RT1Aa) Mouse IgG1 OX-18 Purified Rt C, F, IP
0.1 mg / €270.00
  Acris Antibodies GmbH

MHC Class I (RT1Aa) antibody

MHC Class I (RT1Aa) Mouse IgG1 OX-18 Purified Rt C, F, IP
1 mg / €750.00
  Acris Antibodies GmbH

MHC Class I (RT1Aa) antibody

MHC Class I (RT1Aa) Mouse IgG1 F16-4-4 Purified Rt C, F
0.25 mg / €430.00
  Acris Antibodies GmbH

MHC Class I (RT1Aa) antibody

MHC Class I (RT1Aa) Mouse IgG1 OX-18 Biotin Rt F
0.1 mg / €360.00
  Novus Biologicals Inc.

MHC Class I (RT1Aa) antibody

Flow Cytometry: MHC CLASS I RT1A Antibody (OX-18) [NB100-64215] - Staining of rat spleen cells with MOUSE ANTI RAT RT1A Mouse IgG1 OX-18 FITC Rt F
0.1 mg / €360.00
  Novus Biologicals Inc.

MHC Class I (RT1Aa) antibody

MHC Class I (RT1Aa) Mouse IgG1 F16-4-4 Purified Rt C, F, P
0.25 mg / €380.00
  Novus Biologicals Inc.

MHC Class I (RT1Aa) antibody

Staining of rat spleen cells with MOUSE ANTI RAT RT1A ( CLASS I MONOMORPHIC): FITC Mouse IgG1 OX-18 Purified Rt C, E, F, IP, P
0.1 mg / €320.00
  Novus Biologicals Inc.

11 Item(s)

per page
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