MHC Class I (RT1Au) antibody

Principal name

MHC Class I (RT1Au) antibody

Alternative names for MHC Class I (RT1Au) antibody

RT1-EC2, MHC class I RT1.Au heavy chain

SwissProt ID

Q31256 (Rat)

Ncbi ID


Available reactivities

Rt (Rat)

Available hosts


Available applications

Flow Cytometry (F)

Background of MHC Class I (RT1Au) antibody

MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.

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