MHC Class II I-Ab antibody

Principal name

MHC Class II I-Ab antibody

Alternative names for MHC Class II I-Ab antibody

H2-Eb1, H-2 class II histocompatibility antigen I-A beta chain

SwissProt ID

P18468 (Mouse)

Ncbi ID

10090

Available reactivities

Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rat

Available applications

Flow Cytometry (F), Cytotoxicity Assay (CT), Frozen Sections (C), Paraffin Sections (P), Functional assay (FN)

Background of MHC Class II I-Ab antibody

MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MHC Class II I-Ab antibody

MHC Class II I-Ab Rat IgG2b NIMR-4 PE Ms F
0.2 mg / €400.00
  Acris Antibodies GmbH

MHC Class II I-Ab antibody

MHC Class II I-Ab Rat IgG2b NIMR-4 PE Ms F
0.1 mg / €300.00
  Acris Antibodies GmbH

MHC Class II I-Ab antibody

MHC Class II I-Ab Mouse IgM 25-9-3 PE Ms F
0.1 mg / €320.00
  Acris Antibodies GmbH

3 Item(s)

per page
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