MHC Class II RT1B antibody

Principal name

MHC Class II RT1B antibody

Alternative names for MHC Class II RT1B antibody

HLA Class II, MHC Class 2 RT1B

Available reactivities

Rt (Rat), Ms (Mouse)

Available hosts

Mouse

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P)

Background of MHC Class II RT1B antibody

MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.

General readings

1. McMaster, W. R. and Williams, A. F. (1979) Identification of Ig glycoproteins in rat thymus and purification from rat spleen. Eur. J. Immunol. 9:426-433.
2. Fernandez, J. L. and Weeks, M. (1986) Genetic monitoring of inbred strains of mice using monoclonal antibodies to major histocompatibility haplotypes and lymphocyte alloantigens. Lab. Anim. 20:293-297.
3. Charteris, D. G. and Lightman, S. L. (1993) In vivo lymphokine production in experimental autoimmune uveoretinitis. Immunology. 78(3):387-392.
4. Whiteland, J. L. et al. (1995) Immunohistochemical detection of T-cell subsets and other leucocytes in
paraffin-embedded rat and mouse tissues with monoclonal antibodies. J. Histochem. Cytochem. 43:313-320.
5. McKechnie, N. M. et al. (1997) Immunization with the cross-reactive antigens Ov39 from Onchocerca volvulus
and hr44 from human retinal tissue induces ocular pathology and activates retinal microglia. J. Infect. Dis. 176:1334-1343.
6. Male, D. K. et al. (1987) Serological evidence from a defect in RT1. B (I-A) expression by the BDIX rat strain. J.
Immunogenet. 14(6):301-12.
7. Burrows, G. G. et al. (1998) Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis. J. Immunol. 161:5987-5996

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MHC Class II RT1B antibody

MHC Class II RT1B Mouse IgG1 HIS19 Supernatant Rt C, ICC/IF, IP, P
1 ml / €240.00
  Acris Antibodies GmbH

MHC Class II RT1B (monomorphic) antibody

MHC Class II RT1B Mouse IgG1 OX-6 Biotin Rt F
100 Tests / €440.00
  Acris Antibodies GmbH

MHC Class II RT1B (monomorphic) antibody

Staining of rat spleen cells with Mouse Anti Rat RT1B (Class II Monomorphic): FITC Mouse IgG1 OX-6 FITC Ms, Rt F
0.1 mg / €430.00
  Acris Antibodies GmbH

MHC Class II RT1B (monomorphic) antibody

Staining of rat spleen cells with Mouse Anti Rat RT1B (Class II Monomorphic): FITC Mouse IgG1 OX-6 FITC Ms, Rt F
50 µg / €320.00
  Acris Antibodies GmbH

MHC Class II RT1B (monomorphic) antibody

MHC Class II RT1B Mouse IgG1 OX-6 Purified Rt C, F, P
0.25 mg / €410.00
  Acris Antibodies GmbH

MHC Class II RT1B (monomorphic) antibody

Staining of Rat spleen cells with Mouse anti Rat RT1B MHC class II SM084PS. Mouse IgG1 OX-6 Purified Rt C, F, P
0.1 mg / €270.00
  Acris Antibodies GmbH

MHC Class II RT1B (monomorphic) antibody

Staining of rat spleen cells with mouse anti rat RT1B Mouse IgG1 OX-6 Purified Rt C, F, P, WB
1 mg / €750.00
  Acris Antibodies GmbH

MHC Class II RT1B (monomorphic) antibody

Staining of rat spleen cells with mouse anti rat RT1B: RPE Mouse IgG1 OX-6 PE Ms, Rt F
100 Tests / €530.00
  Acris Antibodies GmbH

MHC Class II RT1B (monomorphic) antibody

MHC Class II RT1B Mouse IgG1 3D6 Rt F, ICC/IF, IP, WB
0.2 mg / €400.00
  Abnova Taiwan Corp.

MHC Class II RT1B (monomorphic) antibody

MHC Class II RT1B Mouse IgG1 3D6 Purified Rt C, F, ICC/IF, IP, WB
1 mg / €330.00
  HyTest Ltd.

MHC Class II RT1B (monomorphic) antibody

Flow Cytometry: MHC CLASS II RT1B Antibody (OX-6) [NB100-64230] - Staining of rat spleen cells with MOUSE ANTI RAT RT1B: FITC Mouse IgG1 OX-6 FITC Ms, Rt F
50 µg / €260.00
  Novus Biologicals Inc.

MHC Class II RT1B (monomorphic) antibody

MHC Class II RT1B Mouse IgG1 OX-6 Biotin Ms, Rt F
100 Tests / €360.00
  Novus Biologicals Inc.

MHC Class II RT1B (monomorphic) antibody

Flow Cytometry: MHC CLASS II RT1B Antibody (OX-6) [NB100-64239] - Staining of rat spleen cells with mouse anti rat RT1B: RPE Mouse IgG1 OX-6 PE Ms, Rt F
50 Tests / €330.00
  Novus Biologicals Inc.

MHC Class II RT1B (monomorphic) antibody

Flow cytometry / FACS analysis: MHC Class II Antibody (OX-6) [NB100-65541] - Staining of rat splenocytes with Mouse anti Rat MHC class II RT1B Mouse IgG1 OX-6 Aff - Purified Ms, Rt C, F, ICC/IF, P, WB
0.25 mg / €340.00
  Novus Biologicals Inc.

MHC Class II RT1B (monomorphic) antibody

MHC Class II RT1B Mouse IgG1 3D6 Purified Rt C, F, ICC/IF, IP, P, WB
0.1 mg / €250.00
  Novus Biologicals Inc.

15 Item(s)

per page
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