mHMG-CoA synthase / HMGCS2 antibody

Principal name

mHMG-CoA synthase / HMGCS2 antibody

Alternative names for mHMG-CoA synthase / HMGCS2 antibody

mitochondrial HMG-CoA synthase, mitochondrial Hydroxymethylglutaryl-CoA synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase

SwissProt ID

O02734 (Pig), P22791 (Rat), P54868 (Human), P54869 (Mouse), Q2KIE6 (Bovin)

Gene ID

3158 (HMGCS2)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of mHMG-CoA synthase / HMGCS2 antibody

HMG-CoA Synthase exists as both a mitochondrial (mHMGCS) and cytoplasmic (cHMGCS) enzyme that condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The HMG-CoA produced by cHMGCS is transformed into mevalote by HMG-CoA reductase, which starts isoprenoid biosynthesis. End products of the isoprenoid pathway include cholesterol, ubiquinone, dolichol, isopentenyl adenosine and farnesyl groups. mHMGCS, together with HMG-CoA Lyase, is responsible for ketone body biosynthesis. mHMGCS is expressed in liver and kidney. Fasting, cAMP and fatty acids increase the level of transcription of mHMGCS, while feeding and insulin repress it. A regulatory element within the mHMGCS promoter confers transcriptiol regulation by PPAR, RXR, COUP-TF and HNF-4.6+.

General readings

Bouchard,L., (2001) Pediatr. Res. 49 (3), 326-331

16 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

mHMG-CoA synthase / HMGCS2 antibody

Western blot analysis of extracts of Fetal liver cell and Caco-2 cell line, using HMGCS2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

mHMG-CoA synthase / HMGCS2 (C-term) antibody

Western blot analysis of HMGCS2 Antibody (C-term) (AP17475PU-N) in HepG2 cell line lysates (35ug/lane). HMGCS2 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

mHMG-CoA synthase / HMGCS2 antibody

Western Blot analysis of HMGCS2 expression in transfected 293T cell line (H00003158-T02) by HMGCS2 MaxPab polyclonal antibody.

Lane 1: HMGCS2 transfected lysate(56.60 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

mHMG-CoA synthase / HMGCS2 antibody

Western Blot analysis of HMGCS2 expression in transfected 293T cell line by HMGCS2 monoclonal antibody (M06), clone 1E9.

Lane 1: HMGCS2 transfected lysate(56.6 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 1E9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

mHMG-CoA synthase / HMGCS2 antibody

Human Jurkat; WB Suggested Anti-HMGCS2 Antibody Titration: 5.0ug/ml. Positive Control: Jurkat cell lysate; HMGCS2 antibody - N-terminal region (ARP41562_T100) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Por, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

mHMG-CoA synthase / HMGCS2 antibody

Human Liver; WB Suggested Anti-HMGCS2 Antibody Titration: 1.25ug/ml. Positive Control: Human Liver; HMGCS2 antibody - C-terminal region (ARP41563_T100) in Human Liver cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

mHMG-CoA synthase / HMGCS2 antibody

Western Blot: HMGCS2 Antibody [NBP1-54869] - This Anti-HMGCS2 antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 5ug/ml. Rabbit Purified Can, Hu, Ms, Rt WB
0.1 mg / €360.00
  Novus Biologicals Inc.

mHMG-CoA synthase / HMGCS2 antibody

Western Blot: HMGCS2 Antibody [NBP1-54995] - This Anti-HMGCS2 antibody was used in Western Blot of Fetal Liver tissue lysate at a concentration of 1.25ug/ml. Rabbit Purified Hu WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

mHMG-CoA synthase / HMGCS2

mHMG-CoA synthase / HMGCS2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

mHMG-CoA synthase / HMGCS2

mHMG-CoA synthase / HMGCS2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

mHMG-CoA synthase / HMGCS2

mHMG-CoA synthase / HMGCS2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

mHMG-CoA synthase / HMGCS2

mHMG-CoA synthase / HMGCS2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

mHMG-CoA synthase / HMGCS2

mHMG-CoA synthase / HMGCS2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

HMGCS2 293T Cell Transient Overexpression Lysate(Denatured)

HMGCS2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

HMGCS2 overexpression lysate

HMGCS2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Lysates (Overexpressed)

Catalog No.    

HMGCS2 overexpression lysate

HMGCS2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

16 Item(s)

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