Mimitin antibody

Principal name

Mimitin antibody

Alternative names for Mimitin antibody

Myc-induced mitochondrial protein, B17.2-like, NDUFAF2, NDUFA12L, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2

SwissProt ID

Q32P65 (Bovin), Q59J78 (Mouse), Q8N183 (Human)

Gene ID

91942 (NDUFAF2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of Mimitin antibody

Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kB-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.

General readings

Tsuneoka M., et al (2005) J. Biol. Chem. 280:19977-19985.
Ogilvie I., et al (2005) J. Clin. Invest. 115:2784-2792.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Mimitin antibody

Western blot analysis of Mimitin in Raji cell lysate with Mimitin antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Mimitin antibody

WB Suggested Anti-NDUFAF2 Antibody; Titration: 1.0 ug/ml; Positive Control: MCF7 Whole Cell Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

Mimitin (C-term) antibody

Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Mimitin Control Peptide

Mimitin
50 µg / €160.00
  Acris Antibodies GmbH

Mimitin antibody

Mimitin Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Mimitin

Mimitin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Mimitin (1-169, His-tag)

Mimitin Human Purified > 85 % E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

Mimitin (1-169, His-tag)

Mimitin Human Purified > 85 % E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Mimitin

Mimitin Human
50 µg / €450.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

NDUFAF2 overexpression lysate

NDUFAF2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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