MIP1 antibody

Principal name

MIP1 antibody

Alternative names for MIP1 antibody

TORC2 subunit MAPKAP1, MAPKAP1, SIN1, mSIN1, SAPK-interacting protein 1, Target of rapamycin complex 2 subunit MAPKAP1, Stress-activated map kinase-interacting protein 1, Mitogen-activated protein kinase 2-associated protein 1

SwissProt ID

A2VDU2 (Bovin), Q6AYF1 (Rat), Q6QD73 (Sheep), Q8BKH7 (Mouse), Q9BPZ7 (Human), Q9W6S3 (Chick)

Gene ID

79109 (MAPKAP1), 227743 (Mapkap1), 296648

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Av (Birds), Bov (Bovine), Chk (Chicken)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of MIP1 antibody

MAPKAP1 was initially identified as the human homolog of S. pombe SIN1. Recent evidence has shown that it identical to Mip1, a protein that interacts with MEKK2, a member of the mitogen-activated protein kinase (MAPK) intracellular signaling network. MAPKAP1 is thought to prevent MEKK2 activation and dimerization by forming a complex with the inactive and non-phosphorylated MEKK2, thereby blocking the JNK1/2, ERK1/2, p38 and ERK5 MAPKs. MAPKAP1 has also been shown to play a role in the TOR signaling process, a pathway that is involved in controlling cell growth and proliferation in response to environmental cues such as nutrients, growth factors and hormones. Experiments showed that MAPKAP1 helped to maintain the TOR/rictor assembly but not the TOR/RAPTOR complex, which allowed specific phosphorylation of Akt, a kinase that is believed to couple the growth factor-PI3K signaling pathway to the nutrient-regulated TOR signaling pathway. Multiple alternatively spliced isoforms of MAPKAP1 have been identified.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MIP1 (N-term) antibody

  Rabbit Polyclonal MAPKAP1 Antibody  
Western blot analysis of MAPKAP1 in human skeletal muscle tissue lysate with MAPKAP1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MIP1 antibody

  Rabbit Polyclonal MAPKAP1 Antibody  
Western blot analysis of MAPKAP1 in human skeletal muscle tissue lysate with MAPKAP1 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MIP1 antibody

  Rabbit Polyclonal anti-MAPKAP1 Antibody  
Hela total cell lysates were resolved by electrophoresis, transferred to nitrocellulose and probed with rabbit anti-MAPKAP1 polyclonal Poly6488. Proteins were visualized using donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence system. Rabbit IgG Poly6488 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MIP1 antibody

  Rabbit Polyclonal anti-MAPKAP1 Antibody  
Hela total cell lysates were resolved by electrophoresis, transferred to nitrocellulose and probed with rabbit anti-MAPKAP1 polyclonal Poly6488. Proteins were visualized using donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence system. Rabbit Poly6488 Purified Hu WB
25 µl / €248.00
  OriGene Technologies, Inc.

MIP1 antibody

Pancreas: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

MIP1 (N-term) antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Brain, Cortex. Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

MAPKAP1 - human gene knockout kit via CRISPR

MAPKAP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MAPKAP1 - human gene knockout kit via CRISPR

MAPKAP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAPKAP1 - human gene knockout kit via CRISPR

MAPKAP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MAPKAP1 - human gene knockout kit via CRISPR

MAPKAP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mapkap1 - mouse gene knockout kit via CRISPR

Mapkap1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Mapkap1 - mouse gene knockout kit via CRISPR

Mapkap1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mapkap1 - mouse gene knockout kit via CRISPR

Mapkap1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

MAPKAP1 overexpression lysate

MAPKAP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

MAPKAP1 overexpression lysate

MAPKAP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

MAPKAP1 overexpression lysate

MAPKAP1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

MAPKAP1 overexpression lysate

MAPKAP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MAPKAP1 (mGFP-tagged) - Human mitogen-activated protein kinase associated protein 1 (MAPKAP1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, MAPKAP1 (mGFP-tagged) - Human mitogen-activated protein kinase associated protein 1 (MAPKAP1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,140.00
  OriGene Technologies, Inc.

Lenti ORF particles, MAPKAP1 (mGFP-tagged)-Human mitogen-activated protein kinase associated protein 1 (MAPKAP1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, MAPKAP1 (mGFP-tagged)-Human mitogen-activated protein kinase associated protein 1 (MAPKAP1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, MAPKAP1 (mGFP-tagged) - Human mitogen-activated protein kinase associated protein 1 (MAPKAP1), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, MAPKAP1 (mGFP-tagged) - Human mitogen-activated protein kinase associated protein 1 (MAPKAP1), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,080.00
  OriGene Technologies, Inc.

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