Mitofusin-2 antibody

Principal name

Mitofusin-2 antibody

Alternative names for Mitofusin-2 antibody

MFN2, CPRP1, KIAA0214, Charcot-Marie-Tooth disease

SwissProt ID

O95140 (Human), Q80U63 (Mouse), Q8R500 (Rat)

Gene ID

9927 (MFN2), 170731 (Mfn2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), African clawed frog, Ze (Zebrafish), Rb (Rabbit), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of Mitofusin-2 antibody

MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. It is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke.This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human MFN2 with an internal ID of P24764

General readings

Chung,K.W., (2008) Neurology 70 (21), 2010-2011

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Mitofusin-2 antibody

  Rabbit polyclonal anti-Mitofusin 2 antibody  
Western blot analysis of Mitofusin 2 in Jurkat cell lysate. Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Mitofusin-2 antibody

  Rabbit anti-MFN2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using MFN2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Mitofusin-2 antibody

  Rabbit Polyclonal Anti-MFN2 Antibody  
WB Suggested Anti-MFN2 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Mitofusin-2 antibody

  Rabbit Polyclonal Anti-MFN2 Antibody  
WB Suggested Anti-MFN2 Antibody Titration: 0.2-1 ug/ml; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Mitofusin-2 antibody

  Rabbit Polyclonal Anti-MFN2 Antibody  
Western blot analysis of MFN2 in human brain tissue lysate with MFN2 antibody at 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Mitofusin-2 antibody

Immunoblot versus crude cardiac mitochondrial preps from WT, Mfn1 KO or Mfn2 KO mice and probed with N153/5 TC supe (top) and Porin antibody (bottom). Data courtesy of Dr. Suzanne Hoppins, Dr. Laura Lackner and Dr. Jodi Nunnari, UCDavis. Mouse IgG2a N153/5 Supernatant Ms, Rt C, ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

Mitofusin-2 antibody

Immunoblot versus crude cardiac mitochondrial preps from WT, Mfn1 KO or Mfn2 KO mice and probed with N153/5 TC supe (top) and Porin antibody (bottom). Data courtesy of Dr. Suzanne Hoppins, Dr. Laura Lackner and Dr. Jodi Nunnari, UCDavis. Mouse IgG2a N153/5 Purified Ms, Rt C, ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Mitofusin-2 (370-600, Cytopl. Dom.) antibody

Mitofusin-2 Mouse IgG2a S153-5 Purified Ms, Rt ICC/IF, P, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

Mitofusin-2 (C-term) antibody

Immunohistochemistry. AP20135PU-N MFN2 antibody  staining of paraffin-embedded rat cardiac muscle tissue. Rabbit IgG Aff - Purified Hu, Ms, Rb, Rt P, WB
0.1 ml / €460.00
  Acris Antibodies GmbH

Mitofusin-2 antibody

Immunohistochemistry (IHC) analyzes of Mfn2 antibody (Cat.-No.: AP20775PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Mitofusin-2 (N-term) antibody

Western blot analysis of rat cardiac muscle tissue lysis using MFN antibody Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Mitofusin-2 (C-term) antibody

Top: MFN2 staining of paraffin-embedded rat cardiac muscle tissue. Bottom: Detection of MFN2 from rat cardiac muscle tissue lysate by Western blot. Rabbit IgG Aff - Purified Hu, Ms, Rb, Rt P, WB
0.1 ml / €460.00
  Neuromics Antibodies

CRISPR

Catalog No. Species Donor Vector  

MFN2 - human gene knockout kit via CRISPR

MFN2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MFN2 - human gene knockout kit via CRISPR

MFN2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MFN2 - human gene knockout kit via CRISPR

MFN2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MFN2 - human gene knockout kit via CRISPR

MFN2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mfn2 - mouse gene knockout kit via CRISPR

Mfn2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Mfn2 - mouse gene knockout kit via CRISPR

Mfn2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mfn2 - mouse gene knockout kit via CRISPR

Mfn2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Mfn2 - mouse gene knockout kit via CRISPR

Mfn2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

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