MLCK2 antibody

Principal name

MLCK2 antibody

Alternative names for MLCK2 antibody

MYLK2, Myosin light chain kinase 2, skeletal, cardiac muscle

SwissProt ID

A4IFM7 (Bovin), P07313 (Rabit), P20689 (Rat), Q8VCR8 (Mouse), Q9H1R3 (Human)

Gene ID

85366 (MYLK2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of MLCK2 antibody

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and myosin light chain kinases (MYLK, also designated MLCK). The MYLK kinases phosphorylate myosin regulatory light chains to catalyze myosin interaction with actin filaments resulting in contractile activity. Non-muscle, smooth muscle and skeletal/cardiac muscle MYLK isoforms exist. The MYLK gene (also designated MYLK1) encodes both smooth muscle and non-muscle isoforms as well as telokin, a small C-terminal isoform expressed only in smooth muscle with the capacity to stabilize unphosphorylated myosin filaments. Multiple transcript variants are described for the MYLK gene. Smooth-muscle and non-muscle MYLK isoforms are expressed in a wide variety of adult and fetal tissues. The skeletal/cardiac muscle isoforms of MYLK are encoded by a separate gene, MYLK2 (also designated skMLCK). MYLK appears to be a target for PAKs (p21-activated kinases). PAK1 interaction with MYLK results in a decrease in MYLK activity and myosin light chain phosphorylation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MLCK2 antibody

MLCK2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

MLCK2 antibody

Western Blot analysis of MYLK2 expression in transfected 293T cell line (H00085366-T01) by MYLK2 MaxPab polyclonal antibody.

Lane 1: MYLK2 transfected lysate(65.56 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

MLCK2 antibody

MLCK2 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

MLCK2 antibody

Western Blot analysis of MYLK2 expression in transfected 293T cell line (H00085366-T02) by MYLK2 MaxPab polyclonal antibody.

Lane 1: MYLK2 transfected lysate(64.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

MLCK2 antibody

Western blot analysis of MYLK2 over-expressed 293 cell line, cotransfected with MYLK2 Validated Chimera RNAi ( Cat # H00085366-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with MYLK2 monoclonal antibody (M01), clone 2G1 (Cat # H00085366-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. Mouse IgG1 2G1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MLCK2

MLCK2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

MLCK2

MLCK2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

MLCK2

MLCK2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

MLCK2

MLCK2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

MLCK2

MLCK2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

MLCK2

MLCK2 Human
0.1 mg / €1,260.00
  Abnova Taiwan Corp.

MLCK2

MLCK2 Human
5 µg / €520.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

MYLK2 293T Cell Transient Overexpression Lysate(Denatured)

MYLK2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

MYLK2 overexpression lysate

MYLK2 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

14 Item(s)

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