MLK4 antibody

Principal name

MLK4 antibody

Alternative names for MLK4 antibody

Mitogen-activated protein kinase kinase kinase, MLK4, KIAA1804

SwissProt ID

Q5TCX8 (Human), Q8VDG6 (Mouse)

Gene ID

84451 (KIAA1804), 234878 (BC021891)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of MLK4 antibody

Mixed-lineage kinases (MLKs) function as mitogen-activated protein kinase kinase kinases (MAP3Ks), activating the p38 and JNK signaling cascades. Systematic mutational analyses of tyrosine kinases reveal that a minimum of 30% of colorectal cancer contain at least one mutation in the tyrosine kinases; sampling of colorect cancer cells suggest an important role of MLK4 in this process. 
Function: Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.

10 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MLK4 antibody

Western blot analysis of extracts from HT-29 cells, using MAP3KL4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MLK4 antibody

Western blot analysis on HT29 cell lysate using MLK4 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MLK4 (N-term) antibody

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with MLK4 Antibody (N-term) Cat.-No AP14913PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MLK4 antibody

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with MLK4 polyclonal antibody ( Cat # PAB3199 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Hu E, P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

MLK4 antibody

Western blot analysis of extracts from HT-29 cells, using MAP3KL4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

MLK4 antibody

Western blot analysis of extracts from HT-29 cells, using MAP3KL4 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

MLK4 antibody

Western Blot: MLK4 Antibody [NBP1-41080]-Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells.  Antibodies: Affinity purified rabbit anti-MLK4 antibody used for IP at 3 mcg/mg lysate.  MLK4 was also immunoprecipitated by rabbit anti-MLK4 antibody NBP1-41081 which recognizes a downstream epitope. Rabbit Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

MLK4 antibody

MLK4 Rabbit Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

MLK4 antibody

Immunohistochemistry-Paraffin: MLK4 Antibody [NBP1-90950] - Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MLK4

MLK4 Human
5 µg / €610.00
  Abnova Taiwan Corp.

10 Item(s)

per page
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