Alternative names for MLL3 antibody
HALR, KIAA1506, KMT2C, Histone-lysine N-methyltransferase MLL3, Myeloid/lymphoid or mixed-lineage leukemia protein 3, Homologous to ALR protein, Lysine N-methyltransferase 2C
Enzyme Immunoassay (E), Western blot / Immunoblot (WB)
Background of MLL3 antibody
MLL3 histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptiol activation. MLL3 is a central component of the MLL2/MLL3 complex, a coactivator complex of nuclear receptors, involved in transcriptiol coactivation. MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.