MLL4 antibody

Principal name

MLL4 antibody

Alternative names for MLL4 antibody

WBP7, HRX2, KIAA0304, KMT2D, MLL2, TRX2, Histone-lysine N-methyltransferase MLL4, Myeloid/lymphoid or mixed-lineage leukemia protein 4, WW domain-binding protein 7, Trithorax homolog 2, Lysine N-methyltransferase 2D

SwissProt ID

O08550 (Mouse), Q9UMN6 (Human)

Gene ID

9757 (MLL4), 75410 (Wbp7)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Por (Porcine)

Available hosts

Rabbit, Mouse, Goat

Available applications

ChIP assay (ChIP), Immunoprecipitation (IP), PLA/Proximity ligation assay (PLA), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C)

Background of MLL4 antibody

This product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognize native protein in any application. This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.

General readings

Huntsman DG, Chin SF, Muleris M, Batley SJ, Collins VP, Wiedemann LM, Aparicio S, Caldas C.
MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines. Oncogene. 1999 Dec 23;18(56):7975-84.
PMID: 10637508

13 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MLL4 (C-term) antibody

(5ug/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Hu, Ms, Rt E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

MLL4 antibody

MLL4 Rabbit IgG Purified Ms E
0.1 ml / €325.00
  OriGene Technologies, Inc.

MLL4 (2703-2715) antibody

Human Testis (formalin-fixed, paraffin-embedded) stained with MLL4 antibody AP22567PU-N followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Eq, Fi, Hu, Mky, Ms, Op, Por, Prim, Rt, Tr, Xen E, P
50 µg / €470.00
  Acris Antibodies GmbH

MLL4 antibody

Detection limit for recombinant GST tagged MLL4 is approximately 0.1ng/ml as a capture antibody. Mouse IgG1 1F6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MLL4 antibody

Detection limit for recombinant GST tagged MLL4 is approximately 0.03ng/ml as a capture antibody. Mouse IgG1 4C10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MLL4 antibody

MLL4 Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

MLL4 antibody

Western blot was performed on whole cell lysates from mouse embryonic stem cells ( E14Tg2a ) with Mll4 polyclonal antibody ( Cat # PAB14067 ), diluted 1 : 500 in PBS-Tween containing 5% skimmed milk.
Cells homozygous for the targeted mll4 allele ( -/-, Lane 2 and 3 ) show a complete loss of Mll4 protein, whereas the Mll4 protein was detected in flp-recombined ES cells ( F/F, Lane 4 ) and heterozygously targeted ES cells ( +/-, Lane 1 ). Rabbit Ms E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

MLL4 antibody

Human HepG2; WB Suggested Anti-MLL4 Antibody Titration: 5ug/ml. Positive Control: HepG2 cell lysate. KMT2B is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells.; MLL4 antibody - N-terminal region (ARP33704_T100) in Human HepG2 cells using Western Blot Rabbit IgG Purified Bov, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

MLL4 antibody

Western blot analysis of MLL4 expression in HL60 (A); A549 (B); NIH3T3 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

MLL4 antibody

Western blot analysis of MLL4 expression in HL60 (A); A549 (B); NIH3T3 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

MLL4 antibody

Western blot analysis of MLL4 expression in HL60 (A); A549 (B); NIH3T3 (C); H9C2 (D) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

MLL4 antibody

Immunohistochemistry-Paraffin: MLL4 Antibody [NB300-864] - (5µg/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat IgG Aff - Purified Hu E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

MLL4 antibody

WB and Immunoprecipitation: TRX-2 Antibody [NB600-254] - Detection of Human Trithorax 2 on HeLa whole cell lysate using NB600-254. Immunoprecipitated TRX2 was detected by WB using either NB600-254 or another rabbit anti-TRX2 antibody. Rabbit Aff - Purified Hu ChIP, IP, PLA, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

13 Item(s)

per page
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