MLLT3 / AF9 antibody

Principal name

MLLT3 / AF9 antibody

Alternative names for MLLT3 / AF9 antibody

YEATS3, Protein AF-9, Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein, ALL1 fused gene from chromosome 9 protein, YEATS domain-containing protein 3

SwissProt ID

A2AM29 (Mouse), P42568 (Human)

Gene ID

4300 (MLLT3)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Ze (Zebrafish), African clawed frog, Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Dot blot (Dot), Immunocytochemistry/Immunofluorescence (ICC/IF), ChIP assay (ChIP)

Background of MLLT3 / AF9 antibody

The human AF9 gene is one of the most common fusion partner genes with the ALL1 gene at 11q23 (also called MLL), resulting in the t(9;11)(p22;q23). The AF9 gene is more than 100 kb, and 2 patient breakpoint cluster regions (BCRs) have been identified; BCR1 is within intron 4, previously called site A, whereas BCR2 or site B spans introns 7 and 8. Several different structural elements have been identified in AF9, including a colocalizing in vivo DNA topo II cleavage site and an in vitro DNase I hypersensitive (DNase 1 HS) site in intron 7 in BCR2. Reversibility experiments demonstrated a religation of the topo II cleavage sites. In addition, 2 scaffold associated regions (SARs) are located centromeric to the topo II and DNase I HS cleavage sites and border breakpoint regions in 2 leukemic cells lines: SAR1 is located in intron 4, whereas SAR2 encompasses parts of exons 5-7. The patient breakpoint regions of AF9 share the same structural elements as the MLL BCR. A DNA breakage and repair model for nonhomologous recombination between MLL and its partner genes, particularly AF9, has been proposed.

General readings

Wei,J., (2008) Cancer Cell 13 (6), 483-495

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MLLT3 / AF9 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MLLT3 / AF9 antibody

WB Suggested Anti-MLLT3 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MLLT3 / AF9 antibody

Anti-MLLT3 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Rabbit Purified Hu E, P
50 µg / €345.00
  OriGene Technologies, Inc.

MLLT3 / AF9 antibody

Host: Rabbit; Target Name: MLLT3; Sample Tissue: 721_B cell lysate; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MLLT3 / AF9 antibody

The anti-MLLT3 Pab is used in Western blot to detect MLLT3 in mouse cerebellum tissue lysate Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MLLT3 / AF9 (N-term) antibody

Western blot analysis of MLLT3 / AF9 Antibody (N-term) Cat.-No AP13159PU-N in HL60 tissue lysate Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MLLT3 / AF9 antibody

Detection limit for recombinant GST tagged MLLT3 is approximately 3ng/ml as a capture antibody. Mouse IgG2a 3C11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

MLLT3 / AF9 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with MLLT3 polyclonal antibody ( Cat # PAB4769 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu E, P
0.4 ml / €390.00
  Abnova Taiwan Corp.

MLLT3 / AF9 antibody

The MLLT3 polyclonal antibody ( Cat # PAB4770 ) is used in Western blot to detect MLLT3 in mouse cerebellum tissue lysate Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

MLLT3 / AF9 antibody

The MLLT3 polyclonal antibody ( Cat # PAB4771 ) is used in Western blot to detect MLLT3 in HL-60 cell lysate Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

MLLT3 / AF9 antibody

Human Hela; Host: Rabbit . Target Name: MLLT3 . Sample Tissue: Hela . Antibody Dilution: 1.0ug/ml. MLLT3 is supported by BioGPS gene expression data to be expressed in HeLa.; MLLT3 antibody - N-terminal region (ARP38489_P050) in Human Hela cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

MLLT3 / AF9 antibody

Western Blot and Immunoprecipitation: AF9 Antibody [NB100-1565] -Detection of Human AF9 on HeLa whole cell lysates using NB100-1565. AF9 was also immunoprecipitated using rabbit anti-AF9 antibodies NB100-1564, NB100-1566 and another AF9 Ab. Rabbit Aff - Purified Hu IP, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

MLLT3 / AF9 antibody

Western Blot and Immunoprecipitation: AF9 Antibody [NB100-1566] -Detection of Human AF9 on HeLa whole cell lysates using NB100-1566. AF9 was also immunoprecipitated using rabbit anti-AF9 antibodies NB100-1564, NB100-1565 and another AF9 Ab. Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

MLLT3 / AF9

MLLT3 / AF9 Purified Hu Dot, ICC/IF, IP, WB
50 µg / €250.00
  Novus Biologicals Inc.

MLLT3 / AF9 antibody

Immunohistochemistry-Paraffin: AF9 Antibody [NBP1-90217] - Immunohistochemical staining of human cerebellum shows strong nuclear positivity in purkinje cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MLLT3 / AF9

MLLT3 / AF9 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

MLLT3 / AF9

MLLT3 / AF9 Human
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

MLLT3 overexpression lysate

MLLT3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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