MMP-13 antibody

Principal name

MMP-13 antibody

Alternative names for MMP-13 antibody

Collagenase 3, MMP13, Matrix metalloproteinase-13

SwissProt ID

O62806 (Rabit), O77656 (Bovin), P23097 (Rat), P33435 (Mouse), P45452 (Human)

Gene ID

4322 (MMP13), 17386 (Mmp13), 171052

Available reactivities

Bov (Bovine), Eq (Equine), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Can (Canine), Chk (Chicken), African clawed frog, Mky (Monkey), Marmoset, Gorilla, Av (Birds), Hst (Hamster), Op (Opossum), Por (Porcine), Sh (Sheep), Bear

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of MMP-13 antibody

Collagenase 3 (MMP13) is a secreted 452 residue protein which is released from cells as aninactive zymogen and activated extracellularly by removal of its propeptide. MMP13 was first identified in tumor cells but has since been found in synoviocytes and normal fibroblasts stimulated by IL6 or a combination of TNF alpha and IL1. Under normal conditions, MMP13 is expressed during embryogenesis (fetal bone development) and is present only at very low levels in adult tissue. However, this enzyme is reported to be involved in the development and metastasis of breast and lung carcinomas, chondrosarcomas and osteosarcomas, head and neck carcinomas and some forms of skin cancer. Additionally, this enzyme plays an important role in degenerative bone diseases including osteoarthritis and rheumatoid arthritis. In rodents, MMP13 is thought to fill the role of MMP1, which they appear to lack.

General readings

Gomis-Rueth F.-X., et al (1996). J. Mol. Biol. 264:556-566
Lausch E., et al (2009). Am. J. Hum. Genet. 85:168-178

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MMP-13 antibody

  MMP13 Mouse Monoclonal Antibody, clone OTI3H3 (formerly 3H3)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-MMP13 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506688) Mouse IgG1 OTI3H3 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

  MMP13 mouse monoclonal antibody, clone OTI1G5 (formerly 1G5)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-MMP13 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506689) Mouse IgG2a OTI1G5 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

  MMP13 mouse monoclonal antibody, clone OTI3A7 (formerly 3A7)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-MMP13 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506693) Mouse IgG2a OTI3A7 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

  MMP13 mouse monoclonal antibody, clone OTI3G1 (formerly 3G1)  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-MMP13 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506723) Mouse IgG2a OTI3G1 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

  MMP13 mouse monoclonal antibody, clone OTI2A6 (formerly 2A6)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-MMP13 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506803) Mouse IgG2a OTI2A6 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

  MMP13 mouse monoclonal antibody, clone OTI2D8 (formerly 2D8)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-MMP13 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506806) Mouse IgG2a OTI2D8 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

  Anti-MMP13 rabbit polyclonal antibody  
Predicted band size: 54kDa. Positive control: Hela cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate:40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MMP-13 antibody

  Rabbit anti-MMP13 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using MMP13 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MMP-13 (N-term) antibody

  Rabbit Polyclonal Anti-MMP13 Antibody (N-Terminus)  
MMP-13 Rabbit IgG Aff - Purified Gorilla, Hu, Marmoset, Mky P
50 µg / €400.00
  OriGene Technologies, Inc.

MMP-13 (internal region) antibody

  Rabbit Polyclonal Anti-MMP13 Antibody (Internal)  
MMP-13 Rabbit IgG Aff - Purified Av, Bear, Bov, Can, Elephant, Eq, Gorilla, Hst, Hu, Marmoset, Mky, Ms, Op, Por, Rb, Rt, Sh P
50 µg / €400.00
  OriGene Technologies, Inc.

MMP-13 antibody

  Rabbit Polyclonal Anti-MMP13 Antibody (C-Terminus)  
Anti-MMP13 antibody IHC of human breast carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu, Mky
50 µg / €400.00
  OriGene Technologies, Inc.

MMP-13 (C-term) antibody

  Rabbit Polyclonal Anti-MMP13 Antibody (C-Terminus)  
MMP-13 Rabbit IgG Aff - Purified Bear, Bov, Can, Elephant, Eq, Hu, Mky, Ms, Por, Rb, Rt, Sh P
50 µg / €400.00
  OriGene Technologies, Inc.

MMP-13 antibody

  MMP13 mouse monoclonal antibody, clone OTI1F1 (formerly 1F1)  
Anti-MMP13 mouse monoclonal antibody (TA506692) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MMP13(RC224156). Mouse IgG1 OTI1F1 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

  MMP13 mouse monoclonal antibody, clone OTI4B3 (formerly 4B3)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-MMP13 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506697) Mouse IgG2a OTI4B3 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

  MMP13 mouse monoclonal antibody, clone OTIF4 (formerly F4)  
Anti-MMP13 mouse monoclonal antibody (TA506699) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MMP13(RC224156). Mouse IgG1 OTIF4 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

  MMP13 mouse monoclonal antibody, clone OTI2D11 (formerly 2D11)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-MMP13 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506719) Mouse IgG2a OTI2D11 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

  MMP13 mouse monoclonal antibody, clone OTI3F5 (formerly 3F5)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-MMP13 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506721) Mouse IgG2a OTI3F5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

  MMP13 mouse monoclonal antibody, clone OTI4B7 (formerly 4B7)  
Anti-MMP13 mouse monoclonal antibody (TA506804) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MMP13(RC224156). Mouse IgG1 OTI4B7 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-13 antibody

MMP-13 Mouse IgG1 181-15A12 Purified Hu C, E, P, WB
0.1 mg / €300.00
  Acris Antibodies GmbH

MMP-13 antibody

Western Blot analysis of MMP13 expression with Jurkat Cell Lysate. Rabbit Aff - Purified Bov, Eq, Hu, Ms, Rb, Rt IP, P, WB
0.1 mg / €370.00
  Acris Antibodies GmbH

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