MMP-18 antibody

Principal name

MMP-18 antibody

Alternative names for MMP-18 antibody

Matrix metalloproteinase-18, MMP18, Collagenase-4, xCol4, col4

SwissProt ID

O13065 (Xenla)

Ncbi ID


Available reactivities

Xen (Xenopus)

Available hosts


Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB)

Background of MMP-18 antibody

All cells within tissues are surrounded by an extracellular matrix (ECM) giving the tissues shape and structure. The ECM is constantly being remodeled and constant communication is maintained between cells through this matrix. Secreted proteins, termed matrix metalloproteinases (MMPs), are involved in the modulation of cell matrix interactions. MMPs are are a family of at least eighteen secreted and membrane bound zinc endopeptidases that degrade various components of the ECM, including fibrillar and non fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. MMPs are enzymes implicated in normal and pathologic tissue remodeling processes, wound healing, angiogenesis, and tumor invasion.

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