MMP-25 antibody

Principal name

MMP-25 antibody

Alternative names for MMP-25 antibody

Matrix metalloproteinase-25, MMP25, MMP20, MMPL1, MT6MMP, Leukolysin, MT6-MMP, MT-MMP 6, Membrane-type matrix metalloproteinase 6

SwissProt ID

Q3U435 (Mouse), Q9NPA2 (Human)

Gene ID

64386 (MMP25)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of MMP-25 antibody

Matrix Metalloproteinase 25, also known as membrane type matrix metalloproteinase 6 and leukolysin, was initially cloned from human leukocytes and found to be specifically expressed by peripheral blood leukocytes. The expression of MMP25 (leukolysin) at the mRNA level appears to be localized to neutrophils. MMP25 was also found in lung, spleen, brain tumors, and several tumor cell lines. Like the other membrane-type metalloproteinases, MMP25 is associated with the cell membrane, but is anchored to the cell surface via a GPI (glycosyl-phosphatidyl inositol) attachment, rather than through a transmembrane domain. MMP25 is proteolytically active and truncated forms digest gelatin in zymograms. Like the other MT MMPs, MMP25 has a furin cleavage site, where prohormone convertases can activate the zymogen. MMP25 can be shed from the from the cell surface, into the culture media under stimulatory conditions. MMP25 is expressed in brain tumors and may facilitate tumor progression through its ability to activate progelatinase A at the cell membrane in colon carcinomas or brain tumors. MMP25 may also play a role in the cellular migration and invasion of the extracellular matrix and basement membranes. The MMP25 gene maps to human chromosome 16p13.3.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MMP-25 antibody

Predicted cell location: Cytoplasm. Positive control: Human brain tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using MMP25 antibody at dilution 1/80, on the right is treated with the synthetic peptide. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

MMP-25 antibody

Predicted band size: 63 kDa . Positive control: 823 cell lysate. Recommended dilution: 1/500-2000 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MMP-25 (C-term) antibody

The anti-MMP25 C-term Antibody is used in Western blot to detect MMP25 in mouse liver tissue lysate (lane 1) and HL60 cell lysate (lane 2) lysate. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MMP-25 antibody

MMP-25 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

MMP-25 antibody

The MMP25 polyclonal antibody ( Cat # PAB4790 ) is used in Western blot to detect MMP25 in mouse liver tissue lysate ( lane 1 ) and HL-60 cell lysate ( lane 2 ) lysate. Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

MMP-25 antibody

Immunohistochemistry-Paraffin: MMP25 Antibody (MM0029-2B5) [NB110-60995] - Human placenta (formalin fixed and paraffin embedded) section is subjected to IHC. Mouse IgG1 MM0029-2B5 Purified Hu P, WB
0.1 mg / €450.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

MMP25 overexpression lysate

MMP25 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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