MMP-25 antibody

Principal name

MMP-25 antibody

Alternative names for MMP-25 antibody

Matrix metalloproteinase-25, MMP25, MMP20, MMPL1, MT6MMP, Leukolysin, MT6-MMP, MT-MMP 6, Membrane-type matrix metalloproteinase 6

SwissProt ID

Q3U435 (Mouse), Q9NPA2 (Human)

Gene ID

64386 (MMP25), 240047 (Mmp25)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of MMP-25 antibody

Proteins of the matrix metalloproteise (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; and tissue remodeling; as well as in disease processes; such as arthritis and metastasis. Most MMPs are secreted as ictive proproteins which are activated when cleaved by extracellular proteises. However; the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation; the encoded protein is thought to ictivate alpha-1 proteise inhibitor; a major tissue protectant against proteolytic enzymes released by activated neutrophils; facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been remed MMP25.

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Lysates

Catalog No.    

MMP25 overexpression lysate

MMP25 overexpression lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

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