MMP-7 antibody

Principal name

MMP-7 antibody

Alternative names for MMP-7 antibody

Matrilysin, Pump-1 protease, Uterine metalloproteinase, Matrix metalloproteinase-7, MMP7, MPSL1, PUMP1, Matrin

SwissProt ID

P09237 (Human), P50280 (Rat), Q10738 (Mouse)

Gene ID

4316 (MMP7)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Fe (Feline), Mky (Monkey), Sh (Sheep), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of MMP-7 antibody

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP\'s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP7 degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP\'s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

General readings

Li YJ, Wei ZM, Meng YX, Ji XR. beta-catenin up-regulates the expression of cyclinD1, c-myc and MMP-7 in human pancreatic cancer: Relationships with carcinogenesis and metastasis.World J Gastroenterol. 2005 Apr 14;11(14):2117-23. PMID: 15810077

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MMP-7 (C-term) antibody

Anti-MMP7 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Rabbit Aff - Purified Hu, Ms, Rt IP, P, WB
50 µg / €345.00
  OriGene Technologies, Inc.

MMP-7 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-MMP7 mouse monoclonal antibody. (UM800061; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min) Mouse IgG1 UMAB168 Purified Hu P
0.1 ml / €379.00
  OriGene Technologies, Inc.

UltraMAB

MMP-7 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-MMP7 mouse monoclonal antibody. (UM800061; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min) Mouse IgG1 UMAB168 Purified Hu P
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

MMP-7 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-MMP7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804842) Mouse IgG1 OTI3G7 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-7 (C-term) antibody

TA302676 (0.03µg/ml) staining of Human Breast lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, P, WB
20 µg / €200.00
  Acris Antibodies GmbH

MMP-7 (C-term) antibody

TA302676 (0.03µg/ml) staining of Human Breast lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MMP-7 antibody

Western blot analysis of extracts from COS7 cells, using MMP-7 antibody (#TA312003).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MMP-7 antibody

Predicted band size: 30 kDa . Positive control: 231 cell lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lysate: 30 ug e Primary antibody: 1/600 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MMP-7 antibody

Western blot analysis of HT29 cell lysate using MMP7 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MMP-7 antibody

Immunohistochemistry: MMP7 Antibody [TA336875] - MMP7 antibody was tested in human breast cancer using DAB with hematoxylin counterstain. The image on the right had the antibody blocked by preincubation with immunizing peptide. Rabbit Purified Hu, Ms C, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

MMP-7 antibody

MMP-7 Rabbit IgG Purified Bov, Eq, GP, Hu, Rb, Sh WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MMP-7 antibody

Western blot analysis on COS7 cell lysate using MMP7 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MMP-7 antibody

Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-MMP7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804870) Mouse IgG2a OTI3E9 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-7 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMP7 (RC201225, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMP7. Mouse IgG1 OTI2E1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-7 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-MMP7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804932) Mouse IgG1 OTI4H8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MMP-7 antibody

Staining of Human ulcerative gastric adenocarcinoma with MMP-7 Antibody Cat.-No AF8210 (Clone 141-7B2) at 2 µg/ml. Antibody positive in cytoplasma. 40x Mouse IgG1 141-7B2 Purified Hu C, E, P, WB
0.1 mg / €300.00
  Acris Antibodies GmbH

MMP-7 antibody

Staining of FFPE Human colon adenocarcinoma (10x and 40x) with MMP-7 Antibody Cat.-No AF9010 (Clone 176-5F12) at 2 µg/ml. Antibody positive in the cytoplasm of neoplastic epithelial cells and in stroma. Mouse IgG1 176-5F12 Purified Hu P, WB
0.1 mg / €300.00
  Acris Antibodies GmbH

MMP-7 antibody

Immunohistochemistry analysis of MMP-7/2 antibody (Cat.-No AP06234PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MMP-7 (132-146) antibody

Figure 1. AP07926PU-N MMP7 antibody staining of Formalin-Fixed Paraffin-Embedded Human Prostate at 10 µg/ml followed by biotinylated Goat anti-Rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

MMP-7 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

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