MMP-9 antibody

Principal name

MMP-9 antibody

Alternative names for MMP-9 antibody

Matrix metalloproteinase-9, MMP9, 92 kDa type IV collagenase, 92 kDa gelatinase, GELB, Gelatinase B, CLG4B

SwissProt ID

P14780 (Human), P41245 (Mouse), P41246 (Rabit), P50282 (Rat), P52176 (Bovin)

Gene ID

4318 (MMP9), 17395 (Mmp9), 81687, 4286 (MITF)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Bov (Bovine), Can (Canine), Chk (Chicken), Rb (Rabbit), Ze (Zebrafish), African clawed frog, GP (Guinea Pig), Marmoset, Xen (Xenopus), Chimp (Chimpanzee), Mky (Monkey), Hst (Hamster)

Available hosts

Mouse, Goat, Rabbit, Sheep, Rat

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP), Functional assay (FN), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of MMP-9 antibody

All cells within tissues are surrounded by an extracellular matrix (ECM) giving the tissues shape and structure. The ECM is constantly being remodeled and constant communication is maintained between cells through this matrix. Secreted proteins, termed matrix metalloproteinases (MMPs), are involved in the modulation of cell matrix interactions. MMPs are Zn(2+) binding endopeptidases that degrade various components of the ECM. MMPs are enzymes implicated in normal and pathologic tissue remodeling processes, wound healing, angiogenesis, and tumor invasion. These enzymes are very potent when active, and are associated with extracellular space inhibitors called TIMPs (tissue inhibitors of matrix metalloproteinases). TIMPs have been shown to block tumor cell invasion suggesting that they act as metastasis suppressor genes. MMP9, also known as gelatinase B, is a secreted enzyme which degrades the interstitial collagens, types I, II, and III and is produced by normal alveolar macrophages and granulocytes. The expression of MMP9 increases in Epstein-Barr virus infected lymphoma derived cell lines and may be of significance in typically invasive nasopharyngeal carcinomas. MMP9 is constitutively produced by some tumor cell lines (e.g.: HT1080, HL60, U937) but not by most quiescent cells and tissues. Treatment of cells with the phorbol ester TPA stimulates production of MMP9 in some cell types, but the low protein levels produced (pg/ml) often require concentration of cell culture media to visualize the bands by Western blotting.

General readings

1. Nikkari ST, et. al. American Journal of Pathology,
1996, 149(5):1427-33.
2 . Soini Y, et. al. Journal of Histochemistry and Cytochemistry,1994, 42(7):945-51.
3. Hurskainen T, et. al. Journal of Histochemistry and Cytochemistry, 1996, 44(12):1379-88.
4. Schnaper HW, et. al. Journal of Cellular Physiology, 1993, 156(2):235-46.
5. Visscher DW, et. al. International Journal of Cancer, 1994, 59(3):339-44.

  1. Quick-Filters:
  2. Cited (1)
  3. Highly Validated (2)
  4. Overnight Delivery (2)

Items 1 to 20 of 77 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MMP-9 antibody

Staining of Human prostatic adenocarcinoma with MMP-9 Antibody Cat.-No AF6910 (Clone 56-2A4) at 2 µg/ml. Antibody positive in cytoplasma and in lumen secreted. 40x Mouse IgG1 56-2A4 Purified Hu C, P, WB
0.1 mg / €300.00
  Acris Antibodies GmbH

MMP-9 antibody

Formalin-Fixed, Paraffin-Embedded Human ovarian carcinoma stained with MMP9 antibody Cat.-No. AM10115SU-N using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining of carcinoma cells. Rabbit IgG EP1255Y Supernatant GP, Hu ICC/IF, P, WB
1 ml / €610.00
  Acris Antibodies GmbH

MMP-9 antibody

Immunohistochemical analysis of paraffin-embedded brain tissues using MMP9 mouse mAb with DAB staining. Mouse IgG2a 5G3 Ascites Hu E, ICC/IF, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

MMP-9 antibody

Western blot analysis using MMP9 mAb against human MMP9 (AA: 238-465) recombinant protein. (Expected MW is 50.6 kDa) Mouse IgG2a 5C3 Ascites Hu E, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

MMP-9 antibody

Human placenta stained with Anti-MMP-9 antibody Rabbit Purified GP, Hu P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

MMP-9 antibody

Human placenta stained with Anti-MMP-9 antibody Rabbit Purified GP, Hu P, WB
1 ml / €440.00
  Acris Antibodies GmbH

MMP-9 antibody

Human placenta stained with Anti-MMP-9 antibody Rabbit Purified GP, Hu P, WB
0.1 ml / €180.00
  Acris Antibodies GmbH

MMP-9 antibody

Western blot analysis of extracts from HeLa cells, using MMP-9 antibody (#TA312179).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MMP-9 antibody

Western blot analysis of MMP-9 in the supernatant of rat MMP transfected cells. Rabbit Purified Rt IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MMP-9 antibody

Western blot analysis on HepG2 cell lysate using MMP9 Antibody Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MMP-9 antibody

MMP-9 Mouse IgG2a S51-82 Purified Hu, Ms, Rt C, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MMP-9 antibody

Western blot analysis of MMP9 in mouse lung tissue lysate with MMP9 antibody at  1 ug/ml. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MMP-9 antibody

Western blot analysis of extracts of mouse spinal cord cell lines, using MMP9 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MMP-9 antibody

Western Blot: MMP9 Antibody (4A3) [TA336901] - Western blot analysis of activated MMP9 expression in MMP9 proenzyme incubated with trypsin for various times. Mouse IgG1 4A3 Purified Hu, Rt C, E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MMP-9 antibody

Anti-MMP9 antibody IHC of human skin, granulation tissue. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Can, Hst, Hu, Mky, Rb
50 µg / €379.00
  OriGene Technologies, Inc.

MMP-9 antibody

Anti-MMP9 antibody IHC of human skin, granulation tissue. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €379.00
  OriGene Technologies, Inc.

MMP-9 antibody

Western blot analysis on HepG2 cell lysate using MMP9 antibody, the lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MMP-9 antibody

MMP-9 Rabbit IgG Purified Hu
50 µg / €325.00
  OriGene Technologies, Inc.

MMP-9 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG2a L51/82 Supernatant Hu, Ms, Rt C, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

MMP-9 antibody

Adult rat hippocampus immunohistochemistry Mouse IgG2a L51/82 Purified Hu, Ms, Rt C, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Items 1 to 20 of 77 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  • LinkedIn