MNDA antibody

Principal name

MNDA antibody

Alternative names for MNDA antibody

Myeloid cell nuclear differentiation antigen

SwissProt ID

P41218 (Human)

Gene ID

4332 (MNDA)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Flow Cytometry (F)

Background of MNDA antibody

The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage.MNDA may act as a transcriptional activator/repressor in the myeloid lineage. It plays a role in the granulocyte/monocyte cell-specific response to interferon. MNDA stimulates the DNA binding of the transcriptional repressor protein YY1.The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Kimkong, I., et al. J. Rheumatol. 37(7):1544-1547(2010)
Kanellis, G., et al. Leukemia 23(10):1847-1857(2009)
Joshi, A.D., et al. Clin. Cancer Res. 13 (18 PT 1), 5295-5304 (2007)
Briggs, R.C., et al. Cancer Res. 66(9):4645-4651(2006)
Asefa, B., et al. FEBS Lett. 580(5):1205-1214(2006)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MNDA antibody

  MNDA mouse monoclonal antibody, clone OTI4H6 (formerly 4H6)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-MNDA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA807178) Mouse IgG2a OTI4H6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

MNDA antibody

  Rabbit polyclonal anti-MNDA antibody  
Western blot analysis of extracts from LOVO cells, using MNDA antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

MNDA antibody

  Rabbit Polyclonal Anti-MNDA Antibody  
WB Suggested Anti-MNDA Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Transfected 293T Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

MNDA antibody

Western blot (WB) analysis of MNDA antibody (Cat.-No.: AP01484PU-N) in extracts from LOVO cells. Rabbit Aff - Purified Hu P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

MNDA (N-term) antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue reacted with MNDA Antibody (N-term) Cat.-No AP52716PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MNDA antibody

Western blot analysis of extracts from LOVO cells, using MNDA Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

MNDA antibody

Western blot analysis of extracts from LOVO cells, using MNDA Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MNDA

  Recombinant protein of human myeloid cell nuclear differentiation antigen (MNDA)  
MNDA Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

MNDA (1-407, His-tag)

MNDA Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €1,500.00
  Acris Antibodies GmbH

MNDA (1-407, His-tag)

MNDA Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €520.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MNDA (mGFP-tagged) - Human myeloid cell nuclear differentiation antigen (MNDA), 200 uL, >10^7 TU/mL

Lenti ORF particles, MNDA (mGFP-tagged) - Human myeloid cell nuclear differentiation antigen (MNDA), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, MNDA (Myc-DDK tagged) - Human myeloid cell nuclear differentiation antigen (MNDA) , 200 uL, >10^7 TU/mL

Lenti ORF particles, MNDA (Myc-DDK tagged) - Human myeloid cell nuclear differentiation antigen (MNDA) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

12 Item(s)

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