MOBKL1B antibody

Principal name

MOBKL1B antibody

Alternative names for MOBKL1B antibody

Mob1 homolog 1B, Mob1 alpha, Protein Mob4B, C2orf6, MOB4B, MOBK1B, Mps one binder kinase activator-like 1B

SwissProt ID

Q3T1J9 (Rat), Q921Y0 (Mouse), Q9H8S9 (Human)

Gene ID

55233 (MOB1A)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F), Frozen Sections (C)

Background of MOBKL1B antibody

MOB1A is an activator of LATS1/2 in the Hippo sigling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kise cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and ictivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. MOB1A stimulates the kise activity of STK38 and STK38L. MOB1A acts cooperatively with STK3/MST2 to activate STK38.

General readings

Chow, A., et al. Int. J. Cancer 126(9):2079-2089(2010)
Wilmeth, L.J., et al. Mol. Biol. Cell 21(3):380-392(2010)
Kosaka, Y., et al. Int. J. Oncol. 31(2):333-338(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MOBKL1B antibody

WB Suggested Anti-MOB1A Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MOBKL1B antibody

WB Suggested Anti-MOB1A Antibody; Titration: 1.0 ug/ml; Positive Control: Jurkat Whole Cell MOB1A is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MOBKL1B (C-term) antibody

Western blot analysis of MOBKL1B antibody (C-term) (AP17563PU-N) in A2058 cell line lysates (35ug/lane). MOBKL1B (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MOBKL1B (N-term) antibody

Western blot analysis of MOBKL1B (arrow) using MOBKL1B Antibody (N-term) Cat.-No AP52718PU-N. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MOBKL1B gene. Rabbit Ig Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MOBKL1B

MOBKL1B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

MOBKL1B

MOBKL1B Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €399.00
  OriGene Technologies, Inc.

MOBKL1B (1-216, His-tag)

Recombinant human MOBKL1B, 1-216 aa, His-tagged Human Purified > 95 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

MOBKL1B (1-216, His-tag)

Recombinant human MOBKL1B, 1-216 aa, His-tagged Human Purified > 95 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

MOBKL1B

MOBKL1B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

MOBKL1B

MOBKL1B Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

MOBKL1B

MOBKL1B Human Purified
0.1 mg / €380.00
  Novus Biologicals Inc.

MOBKL1B

MOBKL1B Human Purified
0.5 mg / €870.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

MOB1A overexpression lysate

MOB1A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

13 Item(s)

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