MOGS / GCS1 antibody

Principal name

MOGS / GCS1 antibody

Alternative names for MOGS / GCS1 antibody

Mannosyl-oligosaccharide glucosidase, Processing A-glucosidase I

SwissProt ID

O88941 (Rat), Q13724 (Human), Q80UM7 (Mouse)

Gene ID

7841 (MOGS), 3157 (HMGCS1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Ze (Zebrafish), African clawed frog, Xen (Xenopus), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of MOGS / GCS1 antibody

Glycosylation of asparagine residues in Asn-X-Ser/Thr motifs in proteins commonly occur in the lumen of the endoplasmic reticulum (ER). Glucosidase I catalyzes the first step in the N-linked oligosaccharide processing pathway. It specifically removes the distal alpha 1,2-linked glucose residue from the Glc3-Man9-GlcNAc2 oligosaccharide precursor. Glucosidase I contains a short cytosolic tail, a single pass transmembrane domain and a large C-terminal catalytic domain located on the luminal side of the ER. Mutations in the gene encoding Glucosidase I result in the congenital disorder glycosylation (CDG-IIb), which is characterized by generalized hypotonia, dysmorphic features, hepatomegaly, hypoventilation, feeding problems, seizures and death. Two point mutations in the Glucosidase I gene have been identified and result in amino acid substitutions, namely Arg486Thr and Phe652Leu, that affect polypeptide folding and active site formation.

General readings

Hardt,B., (2003) Glycobiology 13 (3), 159-168

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MOGS / GCS1 antibody

WB Suggested Anti-GCS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

MOGS / GCS1 (N-term) antibody

Western blot analysis of anti-GCS1 Pab (Cat.#AP12152PU-N) in 293 cell line lysates (35ug/lane). GCS1 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MOGS / GCS1 (C-term) antibody

Western blot analysis of anti-GCS1 Pab (Cat.#AP12153PU-N) in mouse liver cell line lysate (35ug/lane). GCS1(arrow) was detected using the purified Pab. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

MOGS / GCS1 antibody

Western blot analysis of GCS1 polyclonal antibody ( Cat # PAB4279 ) in 293 cell line lysates ( 35 µg/lane ) . GCS1 ( arrow ) was detected using the purified GCS1 polyclonal antibody ( Cat # PAB4279 ) . Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

MOGS / GCS1 antibody

Western blot analysis of GCS1 polyclonal antibody ( Cat # PAB4280 ) in mouse liver tissue lysate ( 35 µg/lane ) . GCS1 ( arrow ) was detected using the purified GCS1 polyclonal antibody ( Cat # PAB4280 ) . Rabbit Hu, Ms E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

MOGS / GCS1 antibody

Human HeLa; WB Suggested Anti-GCS1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Hela cell lysate; GCS1 antibody - N-terminal region (ARP46708_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

MOGS / GCS1 antibody

MOGS / GCS1 Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt, Xen, Ze WB
50 µg / €440.00
  Novus Biologicals Inc.

MOGS / GCS1 antibody

Immunohistochemistry-Paraffin: MOGS Antibody [NBP1-81839] - Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

8 Item(s)

per page
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