MORC3 antibody

Principal name

MORC3 antibody

Alternative names for MORC3 antibody

MORC family CW-type zinc finger protein 3, KIAA0136, ZCWCC3, Zinc finger CW-type coiled-coil domain protein 3

SwissProt ID

Q14149 (Human)

Gene ID

23515 (MORC3)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of MORC3 antibody

MORC3 { m icr orc hidia (MORC) family CW-type zinc finger 3 , KIAA0136, ZCWCC3 and NXP-2}, is a member of the MORC protein family characterized by the conser ved domains consisting of a GHL (Gyrase B, Hsp90 and MutL)-ATPase domain at the N-terminus, a zinc finger type CW domain containing conserved four cysteines and two tryptophans, a nuclear localization signal (NLS) and coiled-coil domains at the C-terminus. There are four MORC family proteins (MORC1, MORC2, MORC3, and MORC4) in human and five (Morc1, Morc2a, Morc2b, Morc3, and Morc4) in mice. MORC1 is expressed specifically in male germ cells, whereas MORC2 and MORC3 in human are ubiquitously expressed. The autosomal recessive mutation of Morc1 in mice causes the arrest of spermatogenesis early in prophase I of meiosis. Takahashi et al . reported that MORC3 is involved in p53 activation and localization of conditionally localized p53 and constitutively localized Sp100 to promyelocytic leukemia (PML)-nuclear bodies (NBs) through its GHL-ATPase activity. MORC3 is localized in PML-nuclear bodies and entire nucleoplasm except for nucleoli.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MORC3 antibody

  Rabbit polyclonal MORC3 Antibody (Center)  
MORC3 Antibody (Center) (Cat. #TA325143) western blot analysis in HL-60 and U87-MG cell line lysates (35ug/lane).This demonstrates the MORC3 antibody detected the MORC3 protein (arrow). Rabbit IgG Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

MORC3 antibody

  Rabbit Polyclonal Anti-MORC3 Antibody  
WB Suggested Anti-MORC3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

MORC3 antibody

Immunocytochemical detection of MORC3 on 4% PFA fixed Saos2 cells with AM26535AF-N. This data was kindly provided by Dr. Norimitsu Inoue. (Department of Molecular Genetics, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Osaka 537-8511, Japan) Mouse IgG1 17A9 Azide Free Hu, Ms, Rt ICC/IF, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

MORC3 - human gene knockout kit via CRISPR

MORC3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

MORC3 - human gene knockout kit via CRISPR

MORC3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

MORC3 - human gene knockout kit via CRISPR

MORC3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

MORC3 - human gene knockout kit via CRISPR

MORC3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MORC3

  Recombinant protein of human MORC family CW-type zinc finger 3 (MORC3)  
MORC3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

MORC3 (full length, C-term DDK tag)

  Purified recombinant protein of Human MORC family CW-type zinc finger 3 (MORC3), full length, with C-terminal DDK tag, expressed in sf9, 20ug  
MORC3 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MORC3 (mGFP-tagged) - Human MORC family CW-type zinc finger 3 (MORC3), 200 uL, >10^7 TU/mL

Lenti ORF particles, MORC3 (mGFP-tagged) - Human MORC family CW-type zinc finger 3 (MORC3), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, MORC3 (Myc-DDK tagged) - Human MORC family CW-type zinc finger 3 (MORC3) , 200 uL, >10^7 TU/mL

Lenti ORF particles, MORC3 (Myc-DDK tagged) - Human MORC family CW-type zinc finger 3 (MORC3) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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