MORF4 antibody

Principal name

MORF4 antibody

Alternative names for MORF4 antibody

CSR, CSRB, SEN, SEN1, mortality factor 4

SwissProt ID

Q9Y690

Gene ID

10934 (MORF4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Ze (Zebrafish), African clawed frog

Available hosts

Chicken, Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of MORF4 antibody

Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to 1 of several complementation groups. MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B.Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to 1 of several complementation groups. MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B.[supplied by OMIM].

General readings

1. Bowman,B.R., Moure,C.M., Kirtane,B.M., Welschhans,R.L., Tominaga,K., Pereira-Smith,O.M. and Quiocho,F.A.
Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain
2. Pardo,P.S., Leung,J.K., Lucchesi,J.C. and Pereira-Smith,O.M., et al.
MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation
3. Yochum,G.S. and Ayer,D.E., et al.
Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split
4. Leung,J.K., Berube,N., Venable,S., Ahmed,S., Timchenko,N. and Pereira-Smith,O.M.
MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14
5. Bertram,M.J., Berube,N.G., Hang-Swanson,X., Ran,Q., Leung,J.K., Bryce,S., Spurgers,K., Bick,R.J., Baldini,A., Ning,Y., Clark,L.J.,, et al.
Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes
6. , Bertram M.J., Berube N.G., Hang-Swanson X., Ran Q., Leung J.K., Bryce S., Spurgers K., Bick R.J., Baldini A., Ning Y., et al.
Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes.
7. , D'Esposito M., Cocchia M., Matarazzo M.R., Macmillan S., Mazzarella R.
Two human homologs of the Drosophila dosage compensation gene msl-3 are located on the X chromosome.
8. , Wan D., Gong Y., Qin W., Zhang P., Li J., Wei L., Zhou X., Li H., Qiu X., Zhong F., et al.
Large-scale cDNA transfection screening for genes related to cancer development and progression.
9. , Guo S., Tong T., Zhang Z.
Cloning and identification of cellular senescence associated genes from fibroblasts 2BS.
10. , Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G., Shen Y., Fan H.-Y., Lu G., et al.
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MORF4 (N-term) antibody

Western blot analysis of MORF4 in K562 cell lysate with MORF4 antibody at (A) 1 and (B) 2 ug/ml. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MORF4 control peptide

MORF4
50 µg / €160.00
  Acris Antibodies GmbH

MORF4 antibody

Immunofluorescence of purified MaxPab antibody to MORF4 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

MORF4 antibody

Immunofluorescence of purified MaxPab antibody to MORF4 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

MORF4 antibody

Immunohistochemistry of MORF4 in human brain tissue with MORF4 polyclonal antibody ( Cat # PAB13005 ) at 5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

MORF4 antibody

Human Muscle; WB Suggested Anti-MORF4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Muscle; MORF4 antibody - middle region (ARP47609_P050) in Human Muscle cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

MORF4 antibody

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-MORF4 ) Chicken Aff - Purified Hu, Ms WB
50 µg / €520.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

MORF4 293T Cell Transient Overexpression Lysate(Denatured)

MORF4 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

8 Item(s)

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