MPG / ANPG antibody

Principal name

MPG / ANPG antibody

Alternative names for MPG / ANPG antibody

DNA-3-methyladenine glycosylase, AAG, ADPG, MID1, 3-methyladenine DNA glycosidase, 3-alkyladenine DNA glycosylase, N-methylpurine-DNA glycosylase

SwissProt ID

P23571 (Rat), P29372 (Human), Q04841 (Mouse)

Gene ID

4350 (MPG)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of MPG / ANPG antibody

MPG(N-methylpurine-DNA glycosylase) also known as MDG, 3-METHYLADENINE DNA GLYCOSYLASE, 3MeAde DNA GLYCOSYLASE, AAG or APNG. The MPG gene is mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines. The MPG gene was expressed in all cell lines and tissues examined, but was found at particularly high levels in a colon adenocarcinoma cell line (HT29). The completely characterized human MPG gene was found to span 7 to 8 kb of genomic DNA and to be localized 75 kb upstream of the embryonic zeta-globin gene. To assess the contribution of Apng to the repair of several mutagenic lesions in vivo, Hang et al. (1997) biochemically analyzed cell-free extracts of tissues from mice with a targeted deletion of the Apng gene. Following treatment with DNA-methylating agents, increased persistence of 7-methylguanine (meG) was found in liver sections of APNG knockout mice in comparison with wildtype mice, demonstrating an in vivo phenotype for the APNG-null animals.

General readings

Samson L, Derfler B, Boosalis M, Call K.
Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16.
Proc Natl Acad Sci U S A. 1991 Oct 15;88(20):9127-31.
PMID: 1924375

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MPG / ANPG (C-term) antibody

  Goat Polyclonal Antibody against MPG  
TA302936 staining (2µg/ml) of K562 lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

MPG / ANPG antibody

  Rabbit anti-MPG Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using MPG antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

MPG / ANPG antibody

  Rabbit Polyclonal Anti-MPG Antibody  
WB Suggested Anti-MPG Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

MPG / ANPG antibody

  Rabbit Polyclonal Anti-MPG Antibody  
WB Suggested Anti-MPG Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

MPG / ANPG antibody

  Rabbit Polyclonal Anti-MPG Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Lovo cells, PC3 cells, Primary antibody: (MPG Antibody) at dilution 1/950, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MPG / ANPG (1-298, His-tag)

MPG / ANPG Human Purified > 90 % E. coli
0.25 mg / €1,000.00
  Acris Antibodies GmbH

MPG / ANPG (1-298, His-tag)

MPG / ANPG Human Purified > 90 % E. coli
50 µg / €370.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

MPG overexpression lysate

MPG overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, MPG (mGFP-tagged)-Human N-methylpurine-DNA glycosylase (MPG), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, MPG (mGFP-tagged)-Human N-methylpurine-DNA glycosylase (MPG), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, MPG (mGFP-tagged)-Human N-methylpurine-DNA glycosylase (MPG), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, MPG (mGFP-tagged)-Human N-methylpurine-DNA glycosylase (MPG), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, MPG (mGFP-tagged) - Human N-methylpurine-DNA glycosylase (MPG), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, MPG (mGFP-tagged) - Human N-methylpurine-DNA glycosylase (MPG), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, MPG (Myc-DDK-tagged)-Human N-methylpurine-DNA glycosylase (MPG), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, MPG (Myc-DDK-tagged)-Human N-methylpurine-DNA glycosylase (MPG), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Lenti ORF particles, MPG (Myc-DDK-tagged)-Human N-methylpurine-DNA glycosylase (MPG), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, MPG (Myc-DDK-tagged)-Human N-methylpurine-DNA glycosylase (MPG), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Lenti ORF particles, MPG (Myc-DDK tagged) - Human N-methylpurine-DNA glycosylase (MPG), transcript variant 3 , 200 uL, >10^7 TU/mL

Lenti ORF particles, MPG (Myc-DDK tagged) - Human N-methylpurine-DNA glycosylase (MPG), transcript variant 3 , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

14 Item(s)

per page
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