MRVI1 / IRAG antibody
Principal name
MRVI1 / IRAG antibody
Alternative names for MRVI1 / IRAG antibody
JAW1-related protein MRVI1, Murine retrovirus integration site 1 protein, Inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
Ncbi ID
ADR83074.1, NM_001098579, NP_001092049, NP_001093633.1, NP_034956.2, NM_010826, NM_194464, NM_130385, NM_001100163
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB)
Background of MRVI1 / IRAG antibody
This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV).The encoded protein, which is found inThe membrane ofThe endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation.This protein is a substrate of cGMP-dependent kise-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by alteringThe expression of a gene important for myeloid cell growth and/or differentiation, and thusThis gene may function as a myeloid leukemia tumor suppressor gene. Several altertively spliced transcript variants encoding different isoforms have been found forThis gene, and altertive translation start sites, including a non-AUG (CUG) start site, are used.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA342098 | MRVI1 / IRAG antibody |
||||||
| Rabbit Polyclonal Anti-MRVI1 Antibody | |||||||
 |
Rabbit | IgG | Purified | Bov, Can, Eq, GP, Hu, Ms, Rb, Rt | WB |
50 µg /
€360.00
|
|
| OriGene Technologies, Inc. | |||||||
CRISPR
| Catalog No. | Species | Donor Vector | |
|---|---|---|---|
| KN215536 | MRVI1 - human gene knockout kit via CRISPR |
||
 |
Human | GFP-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN215536BN | MRVI1 - human gene knockout kit via CRISPR |
||
|
Human | mBFP-Neo |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN215536LP | MRVI1 - human gene knockout kit via CRISPR |
||
|
Human | Luciferase-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN215536RB | MRVI1 - human gene knockout kit via CRISPR |
||
|
Human | RFP-BSD |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN310398 | Mrvi1 - mouse gene knockout kit via CRISPR |
||
|
Mouse | GFP-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP320170 | MRVI1 / IRAG (transcript variant 1) |
||||
| Recombinant protein of human murine retrovirus integration site 1 homolog (MRVI1), transcript variant 1 | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€680.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY420639 | MRVI1 overexpression lysate |
|
|
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. |
Human Lenti ORF Particles
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR221865L2V | Lenti ORF particles, Mrvi1 (GFP-tagged) - Mouse MRV integration site 1 (Mrvi1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,731.00
|
|
| OriGene Technologies, Inc. | ||
| MR221913L2V | Lenti ORF particles, Mrvi1 (GFP-tagged) - Mouse MRV integration site 1 (Mrvi1), transcript variant 2, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,638.00
|
|
| OriGene Technologies, Inc. | ||
| MR221865L1V | Lenti ORF particles, Mrvi1 (Myc-DDK-tagged) - Mouse MRV integration site 1 (Mrvi1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,556.00
|
|
| OriGene Technologies, Inc. | ||
| MR221913L1V | Lenti ORF particles, Mrvi1 (Myc-DDK-tagged) - Mouse MRV integration site 1 (Mrvi1), transcript variant 2, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,473.00
|
|
| OriGene Technologies, Inc. | ||
