MRVI1 / IRAG antibody

Principal name

MRVI1 / IRAG antibody

Alternative names for MRVI1 / IRAG antibody

JAW1-related protein MRVI1, Murine retrovirus integration site 1 protein, Inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate

SwissProt ID

Q9N1F0 (Bovin), Q9WUX5 (Mouse), Q9Y6F6 (Human)

Gene ID

17540 (Mrvi1), 1033515 (C8NKX1), 10335 (MRVI1)

Available reactivities

Ms (Mouse), Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of MRVI1 / IRAG antibody

This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV).The encoded protein, which is found inThe membrane ofThe endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation.This protein is a substrate of cGMP-dependent kise-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by alteringThe expression of a gene important for myeloid cell growth and/or differentiation, and thusThis gene may function as a myeloid leukemia tumor suppressor gene. Several altertively spliced transcript variants encoding different isoforms have been found forThis gene, and altertive translation start sites, including a non-AUG (CUG) start site, are used.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MRVI1 / IRAG antibody

Host: Rabbit; Target Name: MRVI1; Sample Tissue: Thymus Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

MRVI1 / IRAG antibody

MRVI1 / IRAG Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

MRVI1 / IRAG antibody

MRVI1 / IRAG Rabbit Serum Ms ICC/IF, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

MRVI1 / IRAG antibody

Immunohistochemistry-Paraffin: IRAG Antibody [NBP1-87877] - Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

MRVI1 / IRAG (transcript variant 1)

MRVI1 / IRAG Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

MRVI1 overexpression lysate

MRVI1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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